Results 11 to 20 of about 333,011 (338)

An immune-adrenergic pathway induces lethal levels of platelet-activating factor in mice. [PDF]

Commun Biol
Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotransmitters as ...
Tanaka S, Kawakita M, Yasui H, Sudo K, Itoh F, Sasaki M, Shibata N, Hara H, Iwakura Y, Hashidate-Yoshida T, Shindou H, Shimizu T, Oyama T, Matsunaga H, Takahara K.   +14 more
europepmc   +3 more sources

Platelet activating factor

Ensho, 1981
Susumu Otomo
openalex   +4 more sources

Platelet-activating factor receptor in GtoPdb v.2023.1 [PDF]

, 2023
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is an ether phospholipid mediator associated with platelet coagulation, but also subserves inflammatory roles.
Hills, Rebecca, Ishii, Satoshi, Jancar, Sonia, McIntyre, Thomas, Ninio, Ewa, O'Neill, Chris, Oliveira Rios, Francisco Jose, Travers, Jeffery B., Whittaker, Mark   +8 more
core   +2 more sources

Macrophage derived platelet activating factor implicated in the resolution phase of gouty inflammation [PDF]

, 2014
Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Yagnik, Darshna
core   +5 more sources

Augmentation of Staphylococcal α-Toxin Signaling by the Epidermal Platelet-Activating Factor Receptor [PDF]

, 2003
Staphylococcal α-toxin is a cytolytic toxin secreted by many strains of Staphylococcus aureus that has proinflammatory and cytotoxic effects on human keratinocytes. α-toxin exerts its effects by forming a transmembrane pore that behaves like an ionophore
Clay, Keith L., Cosgrove, Jason, Johnson, Christopher, Leung, Donald Y.M., Marques, Mariangela, Schlievert, Patrick, Travers, Jeffrey B.   +6 more
core   +1 more source

Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]

, 2008
Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg, David A, Schmidt, Rene, Staats, Petra, Wagner, Ulrich   +3 more
core   +3 more sources

Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]

, 2005
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Berliner JA, Bittman R, Casals-Stenzal J, Esterbauer H, Fernandez-Ortiz A, Frey B, Goetzl EJ, Holvoet P, Itabe H, Kamido H, Kamido H, Kern H, Kinsella BT, Kitagawa S, O'Flaherty JT, O'Flaherty JT, Rasmussen UB, Sevanian A, Subbanagounder G, Tanaka T, Trip MD, Volf I, Watson AD, Weidtmann A   +23 more
core   +1 more source

Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β(1-42) [PDF]

, 2004
BACKGROUND: Neuronal loss in Alzheimer's or prion diseases is preceded by the accumulation of fibrillar aggregates of toxic proteins (amyloid-β(1-42 )or the prion protein).
Bate, Clive, Salmona, Mario, Williams, Alun   +2 more
core   +2 more sources

Score predictor factor analysis: Reproducing observed covariances by means of factor score predictors [PDF]

Front. Psychol. 10:1895 (2019), 2019
The model implied by factor score predictors does not reproduce the non-diagonal elements of the observed covariance matrix as well as the factor loadings. It is therefore investigated whether it is possible to estimate factor loadings for which the model implied by the factor score predictors optimally reproduces the non-diagonal elements of the ...
arxiv   +1 more source

Radiation therapy generates platelet-activating factor agonists [PDF]

, 2016
Pro-oxidative stressors can suppress host immunity due to their ability to generate oxidized lipid agonists of the platelet-activating factor-receptor (PAF-R).
Chin-Sinex, Helen Jan, Dynlacht, Joseph R., Garrett, Joy Elizabeth, Harrison, Kathleen A., Johnston II., Michael Edward, Konger, Raymond L., Li, Gengxin, McMullen, Kevin, Mendonca, Marc, Murphy, Robert C., Sahu, Ravi P., Spandau, Dan F., Travers, Jeffrey B., Weyerbacher, Jonathan   +13 more
core   +2 more sources