Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao+15 more
wiley +1 more source
Platelet-Activating Factor-Induced Inflammation in Obesity: A Two-Sided Coin of Protection and Risk. [PDF]
Antonopoulou S.
europepmc +1 more source
Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor. [PDF]
Liu J+11 more
europepmc +1 more source
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang+5 more
wiley +1 more source
Platelet-activating factor: a potential therapeutic target to improve cancer immunotherapy. [PDF]
Yan Q, Mohammadpour H.
europepmc +1 more source
Platelet-activating factor and microvesicle particles as potential mediators for the toxicity associated with intoxicated thermal burn injury. [PDF]
Rohan CJ+3 more
europepmc +1 more source
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu+7 more
wiley +1 more source
Is Platelet-Activating Factor the Missing Link Between COVID-19 and Atherosclerosis? [PDF]
Demopoulos CA+2 more
europepmc +1 more source
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study. [PDF]
English CJ+5 more
europepmc +1 more source