Results 251 to 260 of about 1,184,204 (373)

Role of Platelet-Activating Factor in the Pathogenesis of Chronic Spontaneous Urticaria. [PDF]

Int J Mol Sci
Choi BY, Ye YM.
europepmc   +1 more source

Serum Levels of Eosinophil-Derived Neurotoxin, Platelet-Activating Factor and Vascular Endothelial Growth Factor in Adult Patients with Atopic Dermatitis-A Pilot Study. [PDF]

Biomedicines, 2022
Gomułka K, Wójcik E, Szepietowski JC.
europepmc   +1 more source

Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils.

, 1986
T M McIntyre, Guy A. Zimmerman, Stephen M. Prescott   +2 more
openalex   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

Advance in the pathogenesis of otitis media with effusion induced by platelet-activating factor. [PDF]

Sci Prog
Liu W, Shi L, Feng Y.
europepmc   +1 more source

Platelet-activating factor receptor antagonists of natural origin for acute ischemic stroke: a systematic review of current evidence. [PDF]

Front Pharmacol, 2022
Li T, Zhang X, Jiang P, Zhang D, Feng L, Lai X, Qin M, Wei Y, Zhang C, Gao Y.   +9 more
europepmc   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

An increase in the urinary levels of prostaglandin D₂ and platelet-activating factor metabolites in dogs with mast cell tumor. [PDF]

J Vet Med Sci
Yamazaki A, Hayashi A, Nakamura T, Hamasaki Y, Inoue R, Yoshimoto S, Kobayashi K, Nakagawa T, Murata T.   +8 more
europepmc   +1 more source

Structural Modelling of Platelet Activating Factor Acetyl Hydrolase in Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei: Implications on Therapeutics for Leishmaniasis, Chagas Disease, and Sleeping Sickness. [PDF]

Infect Drug Resist, 2023
Goswami A, Koley T, Rajan MV, Madhuri P, Upadhyay N, Das U, Kumar M, Ethayathulla AS, Hariprasad G.   +8 more
europepmc   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source