Results 231 to 240 of about 4,500,208 (289)

Platelet activating factor enhances in vitro fertilization of rabbit oocytes

open access: yesAmerican Journal of Obstetrics and Gynecology, 1990
Capacitation of spermatozoa is essential for fertilization. Rabbit spermatozoa are particularly difficult to capacitate in vitro and require treatment with high-ionic-strength Brackett\u27s defined medium.
B S Minhas   +2 more
exaly   +2 more sources

Identification of Platelet-Activating Factor Acetylhydrolase II in Human Skin [PDF]

open access: yesJournal of Investigative Dermatology, 2002
Platelet-activating factor acetylhydrolases are a family of specialized phospholipase A2 enzymes. They serve an anti-inflammatory function by converting the proinflammatory autocoid, PAF, into biologically inactive lyso-PAF, by the removal of the sn-2 ...
Jeffrey B Travers   +2 more
exaly   +2 more sources

Platelet-activating factor antagonists

Clinical Reviews in Allergy, 1995
The great number of PAF antagonists reviewed in this article clearly shows the tremendous effort made in the last 20 yr to explore the complex biological background of the mechanism of action of PAF and the potential clinical benefit of its antagonists. It is obvious that now highly potent, long-acting, and perorally applicable PAF-receptor antagonists
M, Koltai, P G, Braquet
openaire   +4 more sources

Platelet-Activating Factor

2007
Platelet-activating factor (PAF) is a potent mediator that occurs at very low concentrations in cells and tissues. Accurate quantitation of PAF has always been difficult because of the physicochemical properties of PAF and its structural similarity to several much more abundant phospholipids.
John S, Owen   +2 more
openaire   +3 more sources

Radioimmunoassay for platelet‐activating factor

Lipids, 1991
AbstractA radioimmunoassay (RIA) for measurement of platelet‐activating factor (PAF) was developed. At a final antiserum dilution of 1∶640, the lowest detection limit of PAF was 0.1 pmol (50 pg). The standard curve obtained was suitable for measurement of PAF in amounts ranging from 0.1 pmol to 30 pmol. The antiserum showed high specificity.
K, Karasawa   +5 more
openaire   +2 more sources

Platelet-activating factor receptor

Prostaglandins & Other Lipid Mediators, 2002
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was named for its potential to induce platelet aggregation, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues.
Zen-ichiro, Honda   +2 more
openaire   +3 more sources

Platelet-activating factor and the kidney

American Journal of Physiology-Renal Physiology, 1986
Platelet-activating factor (PAF) represents a group of phospholipids with the basic structure of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine. A number of different cells are capable of producing PAF in response to various stimuli. The initial step of PAF formation is activation of phospholipase A2 in a calcium-dependent manner, yielding lyso-PAF ...
D, Schlondorff, R, Neuwirth
openaire   +2 more sources

PLATELET-ACTIVATING FACTOR IN THE CNS

Progress in Neurobiology, 1996
Platelet-activating factor (PAF) is a phospholipid synthesized in a variety of cells throughout the body. Platelet-activating factor has been identified in the CNS and has a number of diverse physiological and pathological functions. It has been shown to be a modulator of many CNS processes, ranging from long-term potentiation (LTP) to neuronal ...
K M, Maclennan   +2 more
openaire   +2 more sources

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