Results 41 to 50 of about 105,288 (139)

The emerging roles of PAF acetylhydrolase

Journal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre, Stephen M. Prescott, Diana M. Stafforini   +2 more
doaj   +1 more source

High‐dose IVIG plus cangrelor platelet “anesthesia” during urgent heparin‐CPB in a patient with recent SRA‐negative HIT‐thrombosis with persisting platelet‐activating antibodies

Research and Practice in Thrombosis and Haemostasis, 2020
In a high‐risk patient with subacute heparin‐induced thrombocytopenia (HIT) type A (platelet count recovery following acute HIT but with persisting platelet‐activating antibodies), in whom urgent cardiac surgery was required, a key clinical question ...
Andreas Koster, Ishac Nazy, Ingvild E. Birschmann, James W. Smith, Jo‐Ann I. Sheppard, Theodore E. Warkentin   +5 more
doaj   +1 more source

Platelet activating factor acetylhydrolase is associated with cardiac valvular calcification in dialysis patients

Türk Biyokimya Dergisi
The cardiovascular mortality risk is greatly increased in patients with chronic kidney disease (CKD), especially in dialysis patients, due to atherosclerosis.
Bolat Serkan, Fidancı Vildan, Elçik Deniz, Kavraz Tomar Özdem, Murat Sani Namık, Duranay Murat, Yücel Doğan   +6 more
doaj   +1 more source

Semi-synthetic preparation of 1-O-[1'-14C]hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) using plant cell cultures.

Journal of Lipid Research, 1985
Incubation of photomixotrophic cell suspension cultures of rape (Brassica napus) and heterotrophic cell suspension cultures of soya (Glycine max) with 1-O-[1'-14C]hexadecyl-sn-glycerol or rac-1-O-[1'-14C]hexadecylglycerol leads in high yield (up to 78 ...
N Weber, H K Mangold
doaj   +1 more source

Effect of platelet activating factor antagonist treatment on gentamicin nephrotoxicity

Mediators of Inflammation, 1992
To assess whether PAF could be involved in the gentamicin-induced nephrotoxicity, we have studied the effect of PAF antagonist BN-52021 on renal function in rats after gentamicin (GENTA) treatment.
A. Rodriguez-Barbero, E. Bosque, L. Rivas-Cabaero, M. Arévalo, J. M. López-Novoa   +4 more
doaj   +1 more source

Platelet Activating Factor Synthesis and Metabolism in Intestinal Ischaemia-Reperfusion Injury

Mediators of Inflammation, 1994
The object of this study was to characterize the synthesis and metabolism of platelet activating factor (PAF) by intestinal mucosa subjected to ischaemia–reperfusion injury.
M. J. Mangino, M. Murphy, A. Bohrer, J. Turk   +3 more
doaj   +1 more source

Bull Spermatozoa Express Receptors For Platelet-Activating Factor

Revista Científica, 2009
Platelet-activating factor (PAF; 1-O-Alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a ubiquitous phospholipid that is implicated in the mediation of a wide variety of reproductive processes.
Pablo Bosch, William Roudebush, Royal McGraw, Mel DeJarnette, Clifton Marshall, Joe Massey, Benjamin Brackett   +6 more
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Platelet-activating Factor Acetylhydrolases [PDF]

Journal of Biological Chemistry, 1997
D M, Stafforini, T M, McIntyre, G A, Zimmerman, S M, Prescott   +3 more
openaire   +2 more sources

Impact of prostaglandin glaucoma drops on platelet-activating factor action: an in vitro study

Drug Design, Development and Therapy, 2016
Marilita M Moschos,1 Eirini Nitoda,1 Irini P Chatziralli,1 Georgios D Panos,2 Constantinos A Demopoulos3 11st Department of Ophthalmology, Medical School, National and Kapodistrian University of Athens, Athens, Greece; 2Department of Ophthalmology ...
Moschos MM, Nitoda E, Chatziralli IP, Panos GD, Demopoulos CA   +4 more
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Upregulated pneumococcal adhesion molecule (platelet-activating factor receptor) may predispose COPD patients to community-acquired pneumonia

International Journal of COPD, 2017
Shakti Dhar Shukla,1,2 Philip M Hansbro,1,2 Eugene Haydn Walters3 1School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, 2Hunter Medical Research Institute, New Lambton Heights, NSW, 3School of Medicine, University of ...
Shukla SD, Hansbro PM, Walters EH
doaj