Results 81 to 90 of about 24,574 (253)

Platelet-activating Factor (PAF)-dependent Transacetylase and Its Relationship with PAF Acetylhydrolases

open access: yesJournal of Biological Chemistry, 2000
Platelet-activating factor (PAF)-dependent transacetylase (TA) is an enzyme that transfers an acetyl group from PAF to acceptor lipids such as lysophospholipids and sphingosine. This enzyme is distributed in membrane and cytosol of the cells. We previously revealed that TA purified from rat kidney membrane showed an amino acid sequence similarity to ...
K, Bae   +8 more
openaire   +2 more sources

Abstract Supplement

open access: yesPulmonary Medicine, Volume 2026, Issue 1, 2026.

Marzia Folegani, Semonti Nandi
wiley   +1 more source

An immune-adrenergic pathway induces lethal levels of platelet-activating factor in mice

open access: yesCommunications Biology
Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotransmitters as ...
Shuto Tanaka   +14 more
doaj   +1 more source

Expression of a splice variant of the platelet-activating factor receptor transcript 2 in various human cancer cell lines

open access: yesMediators of Inflammation, 2002
Platelet-activating factor receptor (PAF-R) transcripts were analysed by reverse transcriptase-polymerase chain reaction in five human cancer cell lines derived from the breast (BT20, SKBR3 and T47D cells), the pancreas (Miapaca cells) and the bladder ...
Ibtissam Youlyouz   +3 more
doaj   +1 more source

Platelet aggregometry assay for evaluating the effects of platelet agonists and antiplatelet compounds on platelet function in vitro

open access: yesMethodsX, 2019
Platelet aggregometry assays are generally used for the analysis of platelet function but can also be adapted for further research and therapy focused applications.
Alexandros Tsoupras   +2 more
doaj   +1 more source

Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies

open access: yesEuropean Journal of Immunology, Volume 55, Issue 12, December 2025.
Murine allergy model outcomes differ by sensitization route, allergen type, and mouse strain, influencing mechanisms such as IgE and mast cell involvement and the therapeutic relevance of each model. Understanding how experimental parameters shape outcomes is essential for selecting appropriate models and effectively translating findings to clinical ...
Yuka Nagata, Ryo Suzuki
wiley   +1 more source

Impact of prostaglandin glaucoma drops on platelet-activating factor action: an in vitro study

open access: yesDrug Design, Development and Therapy, 2016
Marilita M Moschos,1 Eirini Nitoda,1 Irini P Chatziralli,1 Georgios D Panos,2 Constantinos A Demopoulos3 11st Department of Ophthalmology, Medical School, National and Kapodistrian University of Athens, Athens, Greece; 2Department of Ophthalmology ...
Moschos MM   +4 more
doaj  

Involvement of the α/β Isoform of p38 MAP Kinase in Chemotactic Responses of Human Eosinophils to Eotaxin (CCL11) and RANTES (CCL5) [PDF]

open access: yes, 2017
Eosinophils are the principal effector cells for allergic inflammation in a variety of diseases, in which they contribute to tissue damage and remodelling processes via the secretion of cytotoxic granular proteins and cytokines.
Dent, G, Hasan, AM
core   +2 more sources

Real‐world experience with CPX‐351 for secondary acute myeloid leukaemia: Comparison with FLAG‐IDA in a propensity score matching analysis

open access: yes
British Journal of Haematology, EarlyView.
Maria Agustina Perusini   +19 more
wiley   +1 more source

Long‐Term Real‐World Effectiveness of Rupatadine in Chronic Urticaria: A Retrospective Observational Study

open access: yesJEADV Clinical Practice, Volume 4, Issue 5, Page 1025-1032, December 2025.
This retrospective observational study analyzed a cohort of chronic urticaria (CU) patients to provide insight into the clinical practice of CU with second‐generation antihistamines (SgAHs) and to evaluate the long‐term real‐world effectiveness of rupatadine in CU. Patients with chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU)
A. M. Giménez‐Arnau   +5 more
wiley   +1 more source

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