Advanced Materials, EarlyView.A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao +14 more
wiley +1 more source
Adipose tissue-derived PRXL2A suppresses hepatic lipogenesis in a study with male mice
Nature CommunicationsHepatic de novo lipogenesis (DNL) is crucial for maintaining lipid homeostasis, and its dysregulation is implicated in various metabolic diseases. While it is well established that hepatic DNL is tightly regulated by hormones such as insulin and glucagon
Zhiyuan Li +8 more
doaj +1 more source
Synthesizer: Chemistry‐Aware Machine Learning for Precision Control of Nanocrystal Growth
Advanced Materials, EarlyView.A new, data‐efficient approach to CsPbBr3 nanocrystal optimization combines chemical and physical insights with a Gaussian Process‐based machine learning algorithm. Implementation of the “Synthesizer” enables nm‐precise tuning of the emission wavelength while reducing experimental load in optimizing peak narrowness and photoluminescence quantum yield ...
Nina A. Henke +11 more
wiley +1 more source
Effects of rupatadine, a new dual antagonist of histamine and platelet‐activating factor receptors, on human cardiac Kv1.5 channels [PDF]
, 1999 Ricardo Caballero +4 more
openalex +1 more source
Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]
, 2019 Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul +9 more
core
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells. [PDF]
Int J Mol Sci, 2020 Chauhan SJ +4 more
europepmc +1 more source
BN 52021 (a platelet activating factor‐receptor antagonist) decreases alveolar macrophage‐mediated lung injury in experimental extrinsic allergic alveolitis [PDF]
, 1998 José-Luís Pérez-Arellano +5 more
openalex +1 more source