PET imaging of platelet derived growth factor receptor β in lung fibrosis [PDF]
Background Lung diseases such as idiopathic pulmonary fibrosis and acute respiratory distress syndrome (ARDS) are associated with significant morbidity and mortality, with limited treatment options.
Olivia Wegrzyniak +11 more
doaj +2 more sources
[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways. [PDF]
Hu Y, Cheng P, Ma JC, Xue YX, Liu YH.
europepmc +3 more sources
Platelet-derived growth factor receptor-β as a non-invasive biomarker for liver fibrosis prediction in Egyptian diabetic patients with metabolic-associated fatty liver disease. [PDF]
Badran H +7 more
europepmc +3 more sources
Retracted: Association between the Platelet-Derived Growth Factor/Platelet-Derived Growth Factor Receptor System and Risk of Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. [PDF]
Methods In Medicine CAM.
europepmc +3 more sources
Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity [PDF]
Background Pericytes are a vital component of the blood–brain barrier, and their involvement in acute inflammation was recently suggested. However, it remains unclear whether pericytes contribute to hypothalamic chronic inflammation and energy metabolism
Akira Okekawa +7 more
doaj +2 more sources
Inhibition and Mechanism of Imatinib on A549 Xenograft Tumor in Nude Mice via PDGF/PDGFR Pathway
Objective To investigate the effect of imatinib on the growth of A549 non-small cell lung cancer transplanted tumors and the expression of PDGFB and PDGFRβ proteins in tumor tissues and stroma in nude mice and to explore the underlying tumor suppression ...
XIA Bingtian +6 more
doaj +1 more source
Context: Platelet-rich plasma (PRP) releases growth factors (GFs) upon activation which accelerates the healing and regeneration in the target tissue. Wider applications of PRP warrant product standardization.
Rahul Verma +4 more
doaj +1 more source
Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups [PDF]
BackgroundPlatelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400×103 cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process.
Jeong Woo Lee +8 more
doaj +3 more sources
PDGF-BB homodimer serum level – a good indicator of the severity of alcoholic liver cirrhosis
Introduction Liver cirrhosis is a chronic disease in which progressive fibrosis is noted. This process leads to changed architectonics of the liver parenchyma and the appearance of regenerative nodules, all of which are caused by pathological activation ...
Ewa Kurys-Denis +5 more
doaj +1 more source
Platelet-derived growth factor is one of the major growth factors found in human and mammalian serum and tissues. Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute to ...
Kang Wu +21 more
doaj +1 more source

