Results 1 to 10 of about 375,753 (340)

Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity [PDF]

Molecular Medicine
Background Pericytes are a vital component of the blood–brain barrier, and their involvement in acute inflammation was recently suggested. However, it remains unclear whether pericytes contribute to hypothalamic chronic inflammation and energy metabolism
Akira Okekawa, Tsutomu Wada, Yasuhiro Onogi, Yuki Takeda, Yuichiro Miyazawa, Masakiyo Sasahara, Hiroshi Tsuneki, Toshiyasu Sasaoka   +7 more
doaj   +2 more sources

Inhibition and Mechanism of Imatinib on A549 Xenograft Tumor in Nude Mice via PDGF/PDGFR Pathway

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the effect of imatinib on the growth of A549 non-small cell lung cancer transplanted tumors and the expression of PDGFB and PDGFRβ proteins in tumor tissues and stroma in nude mice and to explore the underlying tumor suppression ...
XIA Bingtian, HE Fang, SONG Bingxin, WANG Lili, ZHU Tingjun, JIA Yongqing, HU Huixian   +6 more
doaj   +1 more source

Growth factors of random butterfly matrices and the stability of avoiding pivoting [PDF]

SIAM Journal on Matrix Analysis and Applications, Volume 44, Issue 3 (2023), 2022
Random butterfly matrices were introduced by Parker in 1995 to remove the need for pivoting when using Gaussian elimination. The growing applications of butterfly matrices have often eclipsed the mathematical understanding of how or why butterfly matrices are able to accomplish these given tasks.
arxiv   +1 more source

Evaluation of factors affecting the quantity and quality of platelet-rich plasma and platelet-derived growth factor-BB

CHRISMED Journal of Health and Research, 2021
Context: Platelet-rich plasma (PRP) releases growth factors (GFs) upon activation which accelerates the healing and regeneration in the target tissue. Wider applications of PRP warrant product standardization.
Rahul Verma, Priyanka Sharma, Gita Negi, Abhishek Kandwal, Harish Chandra   +4 more
doaj   +1 more source

Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups [PDF]

Archives of Plastic Surgery, 2013
BackgroundPlatelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400×103 cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process.
Jeong Woo Lee, O Hyun Kwon, Taek Kyun Kim, Young Kyoo Cho, Kang Young Choi, Ho Yun Chung, Byung Chae Cho, Jung Dug Yang, Jun Ho Shin   +8 more
doaj   +3 more sources

PDGF-BB homodimer serum level – a good indicator of the severity of alcoholic liver cirrhosis

Annals of Agricultural and Environmental Medicine, 2020
Introduction Liver cirrhosis is a chronic disease in which progressive fibrosis is noted. This process leads to changed architectonics of the liver parenchyma and the appearance of regenerative nodules, all of which are caused by pathological activation ...
Ewa Kurys-Denis, Andrzej Prystupa, Dorota Luchowska-Kocot, Witold Krupski, Hanna Bis-Wencel, Lech Panasiuk   +5 more
doaj   +1 more source

Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension

Pulmonary Circulation, 2020
Platelet-derived growth factor is one of the major growth factors found in human and mammalian serum and tissues. Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute to ...
Kang Wu, Haiyang Tang, Ruizhu Lin, Shane G. Carr, Ziyi Wang, Aleksandra Babicheva, Ramon J. Ayon, Pritesh P. Jain, Mingmei Xiong, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Shayan Rahimi, Daniela Valdez-Jasso, Tatum S. Simonson, Ankit A. Desai, Joe G.N. Garcia, John Y.-J. Shyy, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Jason X.-J. Yuan   +21 more
doaj   +1 more source

Expression and function of PDGF-C in development and stem cells

Open Biology, 2021
Platelet-derived growth factor C (PDGF-C) is a relatively new member of the PDGF family, discovered nearly 20 years after the finding of platelet-derived growth factor A (PDGF-A) and platelet-derived growth factor B (PDGF-B).
Yi Tian, Ying Zhan, Qin Jiang, Weisi Lu, Xuri Li   +4 more
doaj   +1 more source

Growth factors of orthogonal matrices and local behavior of Gaussian elimination with partial and complete pivoting [PDF]

SIAM Journal on Matrix Analysis and Applications, Volume 45, Issue 3 (2024), 2023
Gaussian elimination (GE) is the most used dense linear solver. Error analysis of GE with selected pivoting strategies on well-conditioned systems can focus on studying the behavior of growth factors. Although exponential growth is possible with GE with partial pivoting (GEPP), growth tends to stay much smaller in practice.
arxiv   +1 more source

Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway

Haematologica, 2010
Background Platelet-derived growth factor is involved in the regulation of hematopoiesis. Imatinib mesylate, a platelet-derived growth factor receptor inhibitor, induces thrombocytopenia in a significant proportion of patients with chronic myeloid ...
Jie Yu Ye, Godfrey Chi Fung Chan, Liang Qiao, Qizhou Lian, Fan Yi Meng, Xue Qun Luo, Levon M. Khachigian, Ming Ma, Ruixia Deng, Jian Liang Chen, Beng H. Chong, Mo Yang   +11 more
doaj   +1 more source