Results 141 to 150 of about 522,002 (326)

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Olaratumab: a platelet-derived growth factor receptor-α-blocking antibody for the treatment of soft tissue sarcoma

open access: yesClinical Pharmacology: Advances and Applications, 2017
Alexandra Pender,1 Robin L Jones1,2 1Sarcoma Unit, Department of Medicine, The Royal Marsden NHS Foundation Trust, 2Division of Clinical Studies, The Institute of Cancer Research, London, UK Abstract: The outcome of patients with unresectable or ...
Pender A, Jones RL
doaj  

Manufacturing exosomes for wound healing: Comparative analysis of culture media.

open access: yesPLoS ONE
Mesenchymal stem cell (MSC)-derived exosomes (EXs) have emerged as promising therapeutic agents for wound healing. However, the optimal conditions for manufacturing MSC-derived EXs that maximize their wound-healing potential have yet to be established ...
Huy Hoang Dao   +9 more
doaj   +1 more source

Platelet-derived growth factor promotes polymorphonuclear leukocyte activation [PDF]

open access: bronze, 1984
DY Tzeng   +5 more
openalex   +1 more source

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

open access: yesAdvanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro   +5 more
wiley   +1 more source

Vessel stability in the Edinburgh model of retinopathy of prematurity : investigation of mural cell coverage & growth factor expression [PDF]

open access: yes, 2003
Retinal blood vessels consist of endothelial tubules surrounded by a single layer of smooth muscle cells or pericytes, collectively called the mural cells. Coverage of the vessel with mural cells is suggested to signal their stability, and requires the
Yaqoob, Zeenat
core   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

open access: yesAdvanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana   +5 more
wiley   +1 more source

Fibroblast growth factor 1 (FGFR1) modulation regulates repair capacity of oligodendrocyte progenitor cells following chronic demyelination

open access: yesNeurobiology of Disease, 2012
The adult mammalian brain contains multiple populations of endogenous progenitor cell types. However, following CNS trauma or disease, the regenerative capacity of progenitor populations is typically insufficient and may actually be limited by non ...
Yong-Xing Zhou   +3 more
doaj  

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