Results 171 to 180 of about 522,002 (326)

Busy signal: platelet-derived growth factor activation in myelofibrosis

Haematologica, 2020
Anna E. Marneth, Ann Mullally
doaj   +1 more source

Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.

, 1982
Bo Ek, Carl‐Henrik Heldin
openalex   +1 more source

Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects. [PDF]

, 1988
Margaret Bywater, Fredrik Rorsman, Erik Bongcam‐Rudloff, G E Mark, Annet Hammacher, Carl‐Henrik Heldin, Bengt Westermark, Christer Betsholtz   +7 more
openalex   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidan Chen   +21 more
wiley   +1 more source

Phospholipase D activation by the mitogens platelet‐derived growth factor and 12‐O‐tetradecanoylphorbol 13‐acetate in NIH‐3T3 cells [PDF]

, 1989
Pazit Ben-Av, Mordechai Liscovitch
openalex   +1 more source

Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.

, 1982
Carl‐Henrik Heldin, Åke Wasteson, Bengt Westermark   +2 more
openalex   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Stiffness-induced cancer-associated fibroblasts are responsible for immunosuppression in a platelet-derived growth factor ligand-dependent manner. [PDF]

PNAS Nexus, 2023
Gamradt P, Thierry K, Masmoudi M, Wu Z, Hernandez-Vargas H, Bachy S, Antonio T, Savas B, Hussain Z, Tomasini R, Milani P, Bertolino P, Hennino A.   +12 more
europepmc   +1 more source

Human platelet-derived mitogens. I. Identification of insulinlike growth factors I and II by purification and N alpha amino acid sequence analysis [PDF]

, 1989
KP Karey, Hans Marquardt, DA Sirbasku
openalex   +1 more source