Results 21 to 30 of about 530,141 (381)

Role of Platelet-Derived Growth Factors in the Testis [PDF]

Endocrine Reviews, 2010
Normal development and function of the testis are controlled by endocrine and paracrine signaling pathways. Platelet-derived growth factors (PDGFs) are growth factors that mediate epithelial-mesenchymal interactions in various tissues during normal and abnormal processes such as embryo development, wound healing, tissue fibrosis, vascular disorders ...
BASCIANI, Sabrina, Stefania Mariani, G. Spera, GNESSI, Lucio   +3 more
openaire   +4 more sources

Role of Platelet-Derived Growth Factor (PDGF) in Asthma as an Immunoregulatory Factor Mediating Airway Remodeling and Possible Pharmacological Target

Frontiers in Pharmacology, 2020
Asthma is a chronic and heterogenic disease of the respiratory system, one of the most common lung diseases worldwide. The underlying pathologies, which are chronic inflammatory process and airway remodeling (AR), are mediated by numerous cells and ...
Grzegorz Kardas, Agnieszka Daszyńska-Kardas, Mateusz Marynowski, Oliwia Brząkalska, Piotr Kuna, Michał Panek   +5 more
doaj   +1 more source

A Study of the PDGF Signaling Pathway with PRISM [PDF]

, 2011
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway can be analyzed in PRISM.
A. Aziz, A. Gutiérrez-Uzquiza, A. L. Reddi, A. Regev, A. Sadot, C. A. Joazeiro, C. E. Bazenet, C.-H. Heldin, D. Hanahan, E. M. Hahn, Erik de Vink, F. Ciocchetta, G. Krauss, Ion Petre, J. Cools, J. Fisher, J. Fisher, J. Heath, J. Krivine, J. Yu, J. Yu, Jun Pang, K. Anan, K. Yokote, M. Miettinen, M. Schwarick, M. Tallquist, M. Z. Kwiatkowska, M. Z. Kwiatkowska, M. Z. Kwiatkowska, M. Z. Kwiatkowska, Monique Wiesinger, N. Bonzanni, N. Bonzanni, P. Drábik, Panuwat Trairatphisan, Qixia Yuan, S. Hart, S. K. Jha, S. Valgeirsdóttir, Sjouke Mauw, T. Han, T. R. Golub, Thomas Sauter, U.S. Bhalla   +44 more
core   +3 more sources

PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India

Tumor Biology, 2017
Platelet-derived growth factor receptor has been implicated in many malignant and non-malignant diseases. Platelet-derived growth factor receptor-α is a tyrosine kinase and a side target for imatinib, a revolutionary drug for the treatment of chronic ...
Sameer Ahmad Guru, Rashid Mir, Musadiq Bhat, Imtiyaz Najar, Mariyam Zuberi, Mamta Sumi, Mirza Masroor, Naresh Gupta, Alpana Saxena   +8 more
doaj   +1 more source

Quantification of growth factors by using a new system for obtaining platelet-rich plasma [PDF]

, 2011
Objective: To verify the performance of a new method for obtaining platelet-rich plasma, while avoiding contamination of the sample during its processing. Study Design: Twenty healthy patients were selected, from whom 21 ml of blood was extracted.
Lorente Pérez-Sierra, Antonio, López Quiles Martínez, Juan, Martín Ares, María, Martínez González, José María, Ortega Aranegui, Ricardo   +4 more
core   +1 more source

Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study

Journal of Tissue Engineering, 2012
Purpose: Repairing tendon injuries with recombinant human platelet-derived growth factor-BB has potential for improving surgical outcomes. Augmentation of sutures, a critical component of surgical tendon repair, by coating with growth factors may provide
Stephen H Cummings, Daniel A Grande, Christopher K Hee, Hans K Kestler, Colleen M Roden, Neil V Shah, Pasquale Razzano, David M Dines, Nadeen O Chahine, Joshua S Dines   +9 more
doaj   +1 more source

Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury

Neural Regeneration Research, 2021
The blood-spinal cord barrier plays a vital role in recovery after spinal cord injury. The neurovascular unit concept emphasizes the relationship between nerves and vessels in the brain, while the effect of the blood-spinal cord barrier on the ...
Lu-Xia Ye, Ning-Chen An, Peng Huang, Duo-Hui Li, Zhi-Long Zheng, Hao Ji, Hao Li, Da-Qing Chen, Yan-Qing Wu, Jian Xiao, Ke Xu, Xiao-Kun Li, Hong-Yu Zhang   +12 more
doaj   +1 more source

SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines [PDF]

, 2009
CD23 acts through the [alpha]v[beta]5 integrin to promote growth of human pre-B cell lines in an adhesion-independent manner. [alpha]v[beta]5 is expressed on normal B-cell precursors in the bone marrow.
Acharya, M., Cushley, W., Edkins, A.L., Ozanne, B.W.   +3 more
core   +2 more sources

General law of growth and replication. Growth equation and its applications [PDF]

Biophysical Reviews and Letters, 2012 Vol. 7, No. 1-2, p. 71-120, 2012
We present significantly advanced studies of the previously introduced physical growth mechanism and unite it with biochemical growth factors. Obtained results allowed formulating the general growth law which governs growth and evolutional development of all living organisms, their organs and systems.
arxiv   +1 more source

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
A Brar, A Samalecos, A Stavreus-Evers, AA Brahmbhatt, Ana-Maria Bamberger, Anja Wolf, Annemarie Samalecos, AT Fazleabas, B Cloke, B Gellersen, B Gellersen, BA Lessey, Birgit Gellersen, C Ferretti, C Fischer, C Gaggioli, Charlotte H. E. Weimar, CHE Weimar, CM Boomsma, CP Thomas, D Gentilini, D Gentilini, D Haouzi, DE Clark, EE Sander, ER Norwitz, F Chang, F Llorens, F Lyall, G Gaus, G Teklenburg, G Teklenburg, GE Lash, GE Lash, GJ Burton, H Funayama, H Matsumoto, H Xie, HJ Lim, HJ Yoo, I Ihnatovych, IY Yotova, J Anacker, J Baulida, J Fiedler, JJ Brosens, JJ Brosens, JW Tullai, JX Zhu, K Chobotova, K Kawada, K Red-Horse, K Roepstorff, LA Salamonsen, M Bilban, M Bilban, M Cohen, M Gonzalez, M Knöfler, M Knöfler, M Salker, Maren Schwenke, Martin Knöfler, Meijing Wang, Michelle Kruse, MW Maijenburg, Nick S. Macklon, NJ Hannan, NJ Hannan, P Burke, P Jessmon, P Jessmon, P Kaufmann, Philipp Velicky, R Apps, RE Leach, RE Leach, RE Leach, RJ Petrie, RL Kendall, RN Popovici, S Grewal, S Grewal, SK Mitra, Y Jiang, Y Yamazaki   +85 more
core   +8 more sources