Results 31 to 40 of about 522,002 (326)

PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India

open access: yesTumor Biology, 2017
Platelet-derived growth factor receptor has been implicated in many malignant and non-malignant diseases. Platelet-derived growth factor receptor-α is a tyrosine kinase and a side target for imatinib, a revolutionary drug for the treatment of chronic ...
Sameer Ahmad Guru   +8 more
doaj   +1 more source

Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study

open access: yesJournal of Tissue Engineering, 2012
Purpose: Repairing tendon injuries with recombinant human platelet-derived growth factor-BB has potential for improving surgical outcomes. Augmentation of sutures, a critical component of surgical tendon repair, by coating with growth factors may provide
Stephen H Cummings   +9 more
doaj   +1 more source

General law of growth and replication. Growth equation and its applications [PDF]

open access: yesBiophysical Reviews and Letters, 2012 Vol. 7, No. 1-2, p. 71-120, 2012
We present significantly advanced studies of the previously introduced physical growth mechanism and unite it with biochemical growth factors. Obtained results allowed formulating the general growth law which governs growth and evolutional development of all living organisms, their organs and systems.
arxiv   +1 more source

Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]

open access: yes, 2010
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V.   +2 more
core   +2 more sources

Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury

open access: yesNeural Regeneration Research, 2021
The blood-spinal cord barrier plays a vital role in recovery after spinal cord injury. The neurovascular unit concept emphasizes the relationship between nerves and vessels in the brain, while the effect of the blood-spinal cord barrier on the ...
Lu-Xia Ye   +12 more
doaj   +1 more source

A Study of the PDGF Signaling Pathway with PRISM [PDF]

open access: yes, 2011
In this paper, we apply the probabilistic model checker PRISM to the analysis of a biological system -- the Platelet-Derived Growth Factor (PDGF) signaling pathway, demonstrating in detail how this pathway can be analyzed in PRISM.
A. Aziz   +44 more
core   +3 more sources

Hyaluronic acid induces the release of growth factors from platelet-rich plasma

open access: yesAsia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2016
Background/Objective: Platelet-rich plasma (PRP) and hyaluronic acid (HA) injection are both therapeutic options for osteoarthritis and chronic tendinopathy.
Kohei Iio   +7 more
doaj   +1 more source

MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha

open access: yesRespiratory Research, 2021
Background MicroRNA (miR) are small conserved RNA that regulate gene expression post-transcription. Previous genome-wide analysis studies in preterm infants indicate that pathways of miR 219-5p are important in infants with Bronchopulmonary Dysplasia ...
Amelia Freeman   +10 more
doaj   +1 more source

A comparative profile of total protein and six angiogenically-active growth factors in three platelet products

open access: yesGMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2022
Objectives: Platelet-derived products have been shown as promising novel therapeutic agents for chronic wounds. However, their clinical use requires a greater degree of method standardisation, part of which involved more extensive cataloguing of their ...
Custo, Scott   +3 more
doaj   +1 more source

Quantification of growth factors by using a new system for obtaining platelet-rich plasma [PDF]

open access: yes, 2011
Objective: To verify the performance of a new method for obtaining platelet-rich plasma, while avoiding contamination of the sample during its processing. Study Design: Twenty healthy patients were selected, from whom 21 ml of blood was extracted.
Lorente Pérez-Sierra, Antonio   +4 more
core   +1 more source

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