Vascular endothelial growth factor can signal through platelet-derived growth factor receptors [PDF]
Vascular endothelial growth factor (VEGF-A) is a crucial stimulator of vascular cell migration and proliferation. Using bone marrow–derived human adult mesenchymal stem cells (MSCs) that did not express VEGF receptors, we provide evidence that VEGF-A can
Ball, Stephen G.+2 more
core +2 more sources
SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines [PDF]
CD23 acts through the [alpha]v[beta]5 integrin to promote growth of human pre-B cell lines in an adhesion-independent manner. [alpha]v[beta]5 is expressed on normal B-cell precursors in the bone marrow.
Acharya, M.+3 more
core +2 more sources
Experimental supporting data on the influence of platelet-derived factors of malignant pleural effusions on T cell effector functions and their relevance in predicting prognosis of lung adenocarcinoma patients with pleural metastasis [PDF]
The data described in this article are supplementary to our primary article "Platelet factor 4 regulates T cell effector functions in malignant pleural effusions". Malignant pleural effusion (MPE) is a common complication of advanced lung adenocarcinoma (
Calvo, Nuria+9 more
core +1 more source
Effect of NK-104 on proliferation of cells [PDF]
ObjectiveProducts of intracellular mevalonate metabolism are essential for cell growth and proliferation. Inhibition of mevalonate synthesis by statins has been shown to suppress mesangial cell proliferation associated with various glomerular diseases ...
FUNABIKI, Kazuhiko+4 more
core +1 more source
Platelet rich fibrin (PRF) and its related products: biomolecular characterization of the liquid fibrinogen [PDF]
Liquid fibrinogen is an injectable platelet concentrate rich in platelets, leukocytes, and fibrinogen obtained by blood centrifugation. The aim of this study was to analyze the release of different growth factors in the liquid fibrinogen at different ...
De Biase, Alberto+9 more
core +1 more source
Platelet Rich Plasma: Review of Literature [PDF]
Objective: At present, growth factor-containing products such as enamel matrix derivatives, recombinant bone morphogenetic protein (rh-BMP), recombinant platelet derived growth factor and platelet rich plasma (PRP) have gained increasing attention.
Abrishami, Mohammad Reza+2 more
core +2 more sources
The key components of Schwann cell-like differentiation medium and their effects on gene expression pattern of adipose-derived stem cells. [PDF]
BackgroundSchwann cell-like cells differentiated from adipose-derived stem cells may have an important role in peripheral nerve regeneration. Herein, we document the individual effects of growth factors in Schwann cell-like differentiation medium ...
Lankford, Lee+4 more
core +1 more source
Identification of functional VEGF receptors on human platelets [PDF]
Platelets secrete platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) upon stimulation. We have demonstrated that platelets have functionally active PDGF α-receptors, a transmembrane tyrosine kinase involved in negative ...
Holmsen, Holm+2 more
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus [PDF]
The aims were (1) to evaluate the bacteriostatic effect of platelet-rich plasma (PRP), platelet-rich gel (PRG), leukocyte-poor plasma (LPP), leukocyte-poor gel (LPG), plasma, and heat-inactivated plasma (IP) on both methicillin-sensitive Staphylococcus ...
Catalina López+2 more
core +9 more sources