Results 181 to 190 of about 1,682,982 (408)

Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics

Scientific Reports
Distinct platelet activation patterns are elicited by the tyrosine kinase-linked collagen receptor glycoprotein VI (GPVI) and the G-protein coupled protease-activated receptors (PAR1/4) for thrombin.
Delia I. Fernández, Sara Troitiño, Vladimír Sobota, Bibian M. E. Tullemans, Jinmi Zou, Helma van den Hurk, Ángel García, Saman Honarnejad, Marijke J. E. Kuijpers, Johan W. M. Heemskerk   +9 more
doaj   +1 more source

Electrospun silk fibroin fibers for storage and controlled release of human platelet lysate

, 2018
Cataldo Pignatelli, Giovanni Perotto, Marta Nardini, Ranieri Cancedda, Maddalena Mastrogiacomo, Athanassia Athanassiou   +5 more
openalex   +2 more sources

Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib [PDF]

, 2019
Juliet Morgan, Muhammad Saleem, Ruiqi Ng, Caroline Armstrong, Szu Shen Wong, Simon G. Caulton, Alice Fickling, Huw E. L. Williams, Adam D. Munday, José A. López, Mark S. Searle, Jonas Emsley   +11 more
openalex   +1 more source

Prediction of Potential Biomarkers in Early-Stage Nasopharyngeal Carcinoma Based on Platelet RNA Sequencing [PDF]

, 2022
Yuanji Xu, Lin Chen, Yijian Chen, Wangzhong Ye, Xinyi Huang, Mingyao Ke, Guodong Ye, Liancheng Lin, Kangmei Dong, Zhizhong Lin, Penggang Bai, Chuanben Chen   +11 more
openalex   +1 more source

A Robust Heparin‐Mimicking Polyglycerol‐Based Coating for Blood‐Contacting Devices with Long‐Term Hemocompatibility and Preliminary Anti‐Inflammatory Properties

Advanced Healthcare Materials, EarlyView.
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu, Philip Nickl, Jun Feng, Rainer Haag   +3 more
wiley   +1 more source

Improving prediction of fetal/neonatal intracranial hemorrhage in HPA‐1a alloimmunized pregnancies to guide antenatal management: An observational cohort study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Maternal alloimmunization against human platelet antigen‐1a (HPA‐1a) may lead to severe intracranial hemorrhage (ICH) in the fetus or newborn as a life‐threatening complication of fetal neonatal alloimmune thrombocytopenia (FNAIT).
Siw Leiknes Ernstsen, Maria Therese Ahlen, Eirin Listau Bertelsen, Jens Kjeldsen‐Kragh, Anne Husebekk, Heidi Tiller   +5 more
doaj   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Platelet mediated TRAIL delivery for efficiently targeting circulating tumor cells

, 2020
Nerymar Ortiz-Otero, Jocelyn R. Marshall, Bradley W. Lash, Michael R. King   +3 more
openalex   +2 more sources

Formulating Smart All‐in‐One Chitosan Hydrogel for High Performance Wound Dressing

Advanced Healthcare Materials, EarlyView.
An innovative approach to fabricating a thermosensitive, highly swelling, degradable, and antibacterial hydrogel composed of a chitosan‐g‐NIPAAm/PVA/PVP copolymer, integrated with AgNPs, for use in wound dressing applications. The hydrogel demonstrates enhanced performance, accelerating the wound healing process.
Chia‐Chi Lin, Andi Magattang Gafur Muchlis, Ren‐Jei Chung, Ssu Yu Huang, Michal Martinka, Syang‐Peng Rwei, Aivaras Kareiva, Jen‐Chang Yang, Chun Che Lin   +8 more
wiley   +1 more source

Mitochondrial ATP generation in stimulated platelets is essential for granule secretion but dispensable for aggregation and procoagulant activity

Haematologica, 2021
Paresh P. Kulkarni, Mohammad Ekhlak, Vijay K. Sonkar, Debabrata Dash   +3 more
doaj   +1 more source