Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
, 2002 Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S. +3 more
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Platelets and Platelet Phosphatides in Uremia [PDF]
Blood, 1960 Abstract 1. The platelets of 20 uremic subjects were studied, utilizing the following procedures; phase platelet count, serum prothrombin time, thromboplastin generation test with evaluation of plasma, serum, and platelet reagents. 2.
G, ALTSCHULER, A J, MARCUS, H L, ULLMAN
openaire +2 more sources
Anti-platelet therapy: ADP receptor antagonists. [PDF]
, 2011 The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S +3 more
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Serotonin reuptake inhibitors and cardiovascular disease [PDF]
, 2005 Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Noble, M. +2 more
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Platelets and Anti-platelet Therapy
Journal of Pharmacological Sciences, 2003 Platelets play a central role in the hemostatic process and consequently are similarly involved in the pathological counterpart, thrombosis. They adhere to various subendothelial proteins, exposed either by injury or disease, and subsequently become activated by the thrombogenic surface or locally produced agonists.
McNicol, Archibald, Israels, Sara J.
openaire +4 more sources
Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]
, 2005 Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Siedler, F. +3 more
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Investigations into effects of 12-lipoxygenase and NADPH oxidase on platelet activity, and influences of dietary dark chocolate [PDF]
, 2012 PhDPlatelets play a pivotal role in both normal hemostasis and pathological bleeding and importantly also contribute to the development of atherothrombosis.
Zain, Zetty Nadia Mohd
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Platelet adhesion in atherogenesis [PDF]
, 2010 A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
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Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
, 2008 Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
David A Groneberg +12 more
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Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]
, 2000 A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Bondy, Brigitta +11 more
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