Results 21 to 30 of about 504,301 (176)
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
, 2013 When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source
Effects of Average Number of Platelets Through the Thickness and Platelet Width on the Mechanical Properties of Discontinuous Fiber Composites [PDF]
arXiv, 2023 In this study, we experimentally and numerically investigate the evolution of the tensile material properties of Discontinuous Fiber Composites (DFCs) with an increasing average number of platelets through the thickness for two different platelet widths.
arxiv
Permeability and conductivity of platelet-reinforced membranes and composites [PDF]
, 2001 We present large scale simulations of the diffusion constant $D$ of a random composite consisting of aligned platelets with aspect ratio $a/b>>1$ in a matrix (with diffusion constant $D_0$) and find that $D/D_0 = 1/(1+ c_1 x + c_2 x^2)$, where $x= a v_f/b$ and $v_f$ is the platelet volume fraction.
arxiv +1 more source
Bulk fluid phase behaviour of colloidal platelet-sphere and platelet-polymer mixtures [PDF]
, 2012 Using a geometry-based fundamental measure density functional theory, we calculate bulk fluid phase diagrams of colloidal mixtures of vanishingly thin hard circular platelets and hard spheres. We find isotropic-nematic phase separation with strong broadening of the biphasic region upon increasing the pressure.
arxiv +1 more source
A Wigner-Seitz model of charged lamellar colloidal dispersions [PDF]
Phys. Rev. E 56, 3137 (1997)., 1997 A concentrated suspension of lamellar colloidal particles (e. g. clay) is modelled by considering a single, uniformly charged, finite platelet confined with co- and counterions to a Wigner-Seitz (WS) cell. The system is treated within Poisson-Boltzmann theory, with appropriate boundary conditions on the surface of the WS cell, supposed to account for ...
arxiv +1 more source
Bleeding, Thrombosis and Vascular Biology, 2023 The platelet collagen receptor glycoprotein VI (GPVI) signals to activation of phospholipase Cγ2 (PLCγ2) and phosphoinositide 3-kinases (PI3K), causing platelet activation and aggregation.
Jingnan Huang +5 more
doaj +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, EarlyView.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
The Perspectives of Platelet Proteomics in Health and Disease
BiomedicinesCardiovascular thromboembolic diseases and cancer continue to be a leading cause of death and disability worldwide. Therefore, it is crucial to advance their diagnoses and treatment in the context of individualized medicine.
Preeti Kumari Chaudhary +3 more
doaj +1 more source
Journal of Traditional and Complementary Medicine, 2018 Platelets play a key role in thrombosis and cardiovascular diseases. Medicinal plants could be one of the most important factors that influence risks for platelet activation.
Manuel Fuentes +4 more
doaj +1 more source
Potential predictors for chemotherapeutic response and prognosis in epithelial ovarian, fallopian tube and primary peritoneal cancer patients treated with platinum-based chemotherapy [PDF]
Obstetrics & Gynecology Science, 2020 ObjectiveThis study aimed to investigate the potential predictive factors for platinum resistance and poor prognosis in epithelial ovarian, fallopian tube, and primary peritoneal cancer treated with platinum-based chemotherapy.MethodsMedical records of ...
Dhammapoj Jeerakornpassawat +1 more
doaj +1 more source