Results 11 to 20 of about 467,395 (313)
Platelet Biochemistry and Morphology after Cryopreservation [PDF]
, 2020 Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle +2 more
core +1 more source
Frontiers in Immunology, 2022 BackgroundChancre self-healing, a typical clinical phenomenon of primary syphilis, is essentially wound healing. The first response to a wound is constriction of the injured blood vessels and activation of platelets to form a fibrin clot.
Qiu-Yan Xu +9 more
doaj +1 more source
, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
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Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1985 Platelets are discoidal cytoplasmic particles that respond to a variety of stimuli by developing filopodia and rounding up (shape change), developing the ability to bind fibrinogen from the medium, and, with strong stimuli such as thrombin and PAF-acether, secreting the contents of several types of granules.
M B, Zucker, V T, Nachmias
openaire +2 more sources
Platelet surface-associated activation and secretion-mediated inhibition of coagulation factor XII. [PDF]
PLoS ONE, 2015 Coagulation factor XII (fXII) is important for arterial thrombosis, but its physiological activation mechanisms are unclear. In this study, we elucidated the role of platelets and platelet-derived material in fXII activation.
Natalia V Zakharova +6 more
doaj +1 more source
TH Open, 2023 Background Patients with systemic lupus erythematosus (SLE) have an increased risk of thrombosis even when they do not have antiphospholipid syndrome (APS). Interactions between complement activation and activated platelets have been suggested in SLE and
Signe Risbøl Vils +3 more
doaj +1 more source
Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3 [PDF]
, 2016 Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human ...
Arman, Mònica +5 more
core +4 more sources
HIV-1 induces in vivo platelet activation by enhancing platelet NOX2 activity. [PDF]
, 2015 OBJECTIVES: HIV-1 patients show increased platelet activation, but the mechanisms involved are not completely clarified. We speculated that HIV-1 might induce in vivo platelet activation by enhancing platelet NOX2-related oxidative stress.
Bartimoccia, Simona +9 more
core +1 more source
Frontiers in Molecular Biosciences, 2023 Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood.Methods: To explore the molecular profile of AD and aged ...
Diana M. Bessa de Sousa +29 more
doaj +1 more source
Platelets and infection — an emerging role of platelets in viral infection
Frontiers in Immunology, 2014 Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis. While platelet activation and elevated platelet counts (thrombocytosis) are associated with increased risk of thrombotic complications, low platelet counts ...
Alice eAssinger, Alice eAssinger
doaj +1 more source