Results 11 to 20 of about 4,112,530 (307)

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor [PDF]

, 2014
Introduction Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood.
Crooks, Michael, Crooks, Michael G., Fahim, Ahmed, Hart, Simon, Hart, Simon P., Morice, Alyn, Morice, Alyn H., Naseem, Khalid, Naseem, Khalid M.   +8 more
core   +7 more sources

The Outer Membrane Lipoprotein Tp0136 Stimulates Human Platelet Activation and Aggregation Through PAR1 to Enhance Gq/Gi Signaling

Frontiers in Immunology, 2022
BackgroundChancre self-healing, a typical clinical phenomenon of primary syphilis, is essentially wound healing. The first response to a wound is constriction of the injured blood vessels and activation of platelets to form a fibrin clot.
Qiu-Yan Xu, Qiu-Yan Xu, Yong-Jing Wang, Yong-Jing Wang, Li-Rong Lin, Li-Rong Lin, Li-Li Liu, Li-Li Liu, Tian-Ci Yang, Tian-Ci Yang   +9 more
doaj   +1 more source

Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates. [PDF]

PLoS ONE, 2017
BACKGROUND:Previous studies have shown that flow cytometry is a reliable test to quantify platelet function in stored platelet concentrates (PC). It is thought that flow cytometry is laborious and hence expensive.
Cécile H Kicken, Mark Roest, Yvonne M C Henskens, Bas de Laat, Dana Huskens   +4 more
doaj   +1 more source

Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3 [PDF]

, 2016
Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human ...
Arman, Mònica, Cox, Dermot, Henderson, Ian R., Kerrigan, Steven W., Watson, Callum N., Watson, Steve P.   +5 more
core   +3 more sources

Preeclampsia and platelets activation

Platelets, 2019
Dear Sir,We found the metanalysis by Jakobsen et al. regarding the function of platelets in preeclampsia (PE) very interesting [1].
Antonio Ponzetto, Giovanna Turvani
openaire   +5 more sources

Platelet surface-associated activation and secretion-mediated inhibition of coagulation factor XII. [PDF]

PLoS ONE, 2015
Coagulation factor XII (fXII) is important for arterial thrombosis, but its physiological activation mechanisms are unclear. In this study, we elucidated the role of platelets and platelet-derived material in fXII activation.
Natalia V Zakharova, Elena O Artemenko, Nadezhda A Podoplelova, Anastasia N Sveshnikova, Irina A Demina, Fazly I Ataullakhanov, Mikhail A Panteleev   +6 more
doaj   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Platelets and the Lectin Pathway of Complement Activation in Patients with Systemic Lupus Erythematosus or Antiphospholipid Syndrome

TH Open, 2023
Background Patients with systemic lupus erythematosus (SLE) have an increased risk of thrombosis even when they do not have antiphospholipid syndrome (APS). Interactions between complement activation and activated platelets have been suggested in SLE and
Signe Risbøl Vils, Anne Troldborg, Anne-Mette Hvas, Steffen Thiel   +3 more
doaj   +1 more source

HIV-1 induces in vivo platelet activation by enhancing platelet NOX2 activity. [PDF]

, 2015
OBJECTIVES: HIV-1 patients show increased platelet activation, but the mechanisms involved are not completely clarified. We speculated that HIV-1 might induce in vivo platelet activation by enhancing platelet NOX2-related oxidative stress.
Bartimoccia, Simona, Carnevale, Roberto, Di Campli, Francesco, Esposito, Antonella, Fantauzzi, Alessandra, Mezzaroma, Ivano, Novo, Marta, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +9 more
core   +1 more source