Results 221 to 230 of about 491,468 (315)

Platelet activation in breast cancer: mechanisms and therapeutic opportunities - a narrative review. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Cytotoxic Effect of Activated Platelets on Endothelial Cells.

, 1995
Fujío Numano, Yukio Kishi
openalex   +2 more sources

Functional Characterization of the Promoter Region of the Platelet-activating Factor Receptor Gene. [PDF]

, 1995
Jong‐Hwei S. Pang, Ru-Ying Hung, Chia‐Jung Wu, Yaw-Yeu Fang, Lee‐Young Chau   +4 more
openalex   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

The Effects of Inclisiran on the Subclinical Prothrombotic and Platelet Activation Markers in Patients at High Cardiovascular Risk. [PDF]

J Cardiovasc Dev Dis
Maligłówka M, Dec A, Bułdak Ł, Okopień B.   +3 more
europepmc   +1 more source

Pathway of phospholipase C activation initiated with platelet-derived growth factor is different from that initiated with vasopressin and bombesin.

, 1988
Hiroko Hasegawa‐Sasaki, F. Lutz, T Sasaki   +2 more
openalex   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Metabolic Reprogramming in Toll-like Receptor-Mediated Platelet Activation. [PDF]

Cells
Cheah LT, Khalil JS, McKay M, Ali M, Duval C, Unsworth AJ, Naseem KM.   +6 more
europepmc   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Biomechanical platelet activation: diseases that require a new class of antiplatelet therapeutics. [PDF]

Am J Physiol Cell Physiol
Gupta R, Alkhalfan F, Wheeler J, Cameron SJ.   +3 more
europepmc   +1 more source