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Platelets and infection — an emerging role of platelets in viral infection
Frontiers in Immunology, 2014 Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis. While platelet activation and elevated platelet counts (thrombocytosis) are associated with increased risk of thrombotic complications, low platelet counts ...
Alice eAssinger, Alice eAssinger
doaj +1 more source
PD-L1 Regulates Platelet Activation and Thrombosis via Caspase-3/GSDME Pathway
Frontiers in Pharmacology, 2022 Platelets play a central role in hemostasis and thrombosis, regulating the occurrence and development of thrombotic diseases, including ischemic stroke. Programmed death ligand 1 (PD-L1) has recently been detected in platelet, while the function of PD-L1
Yulong Li +13 more
doaj +1 more source
, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core +1 more source
Flow-induced platelet activation in components of the extracorporeal membrane oxygenation circuit
Scientific Reports, 2018 Extracorporeal membrane oxygenation (ECMO) is used for rescue in severe respiratory and/or circulatory failure. The patient’s blood is pumped over artificial surfaces in the ECMO circuit.
G. Fuchs +3 more
semanticscholar +1 more source
Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]
, 2020 Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv +1 more source
Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor [PDF]
, 2014 Introduction Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood.
Crooks, Michael +8 more
core +3 more sources
Blood, 2017 Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show in a tissue factor (TF)-dependent model of flow restriction-induced venous thrombosis that ...
S. Subramaniam +9 more
semanticscholar +1 more source
Digoxin and platelet activation in patients with atrial fibrillation: In vivo and in vitro study [PDF]
, 2018 Background-Digoxin use was shown to be associated with an increased risk of cardiovascular events in atrial fibrillation (AF). We hypothesized that digoxin may affect cardiovascular risk by increasing platelet activation.
Bartimoccia, Simona +10 more
core +1 more source
Combined Effect of Acute Altitude Exposure and Vigorous Exercise on Platelet Activation [PDF]
, 2022 Exposure to high altitudes and exercise alters body's physiology and may cause acute cardiovascular events. Platelet activation is one of the key players in these events. Therefore, we investigated the effect of vigorous exercise at higher altitude (2650
Brunner, Stefan +5 more
core +1 more source
BMC Medicine, 2020 Background Antiretroviral therapy (ART) alters platelet reactivity, and as a consequence, patients living with HIV may be at an increased risk of cardiovascular disease (CVD).
Bongani B. Nkambule +6 more
doaj +1 more source