Results 251 to 260 of about 12,292 (326)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Advancements in nanomedicine for modulating ischemic cardiomyopathy therapy. [PDF]

open access: yesMater Today Bio
Ren X   +5 more
europepmc   +1 more source

Synergistic SnSe2@Ti3C2Tx MXene Heterostructured Separator for Highly Efficient Polysulfide Adsorption, Catalytic Redox Acceleration, and Enhanced Electrochemical Stability in Advanced Lithium–Sulfur Batteries

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A multifunctional SnSe2@MXene heterostructure coated on a separator serves as a catalytic interlayer in Li‐S batteries. This design synergistically integrates the strong polysulfide adsorption and catalytic activity of SnSe2 with the high electrical conductivity of the MXene matrix, effectively suppressing the shuttle effect and enabling long‐term ...
Amirhossein Mirtaleb   +2 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Platelets and diseases: signal transduction and advances in targeted therapy. [PDF]

open access: yesSignal Transduct Target Ther
Tian Y   +6 more
europepmc   +1 more source

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk   +12 more
wiley   +1 more source

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