Results 81 to 90 of about 1,089,521 (397)

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song   +6 more
wiley   +1 more source

CYP2C19*17 Polymorphisms And Platelet Aggregation In Coronary Artery Disease Patients With Clopidgrel [PDF]

open access: yes, 2017
Background: Clopidogrel is the alternative therapy for patients with Coronary Artery Disease (CAD) that couldn’t use Aspirin as antiplatelet. There’s some factors that contribute to clopidogrel effectiveness, such as obesity, Diabetes Mellitus, Smoking,
Ananda, Yuki   +2 more
core  

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani   +38 more
wiley   +1 more source

PLATELET AGGREGATION PROFILE AND CARDIOVASCULAR EVENT IN CORONARY HEART DISEASE PATIENTS WITH DUAL ANTIPLATELET [PDF]

open access: yes, 2016
Platelet aggregation plays an important role in atherosclerosis process in Coronary Heart Disease (CHD) patients. Antiplatelet acts to prevent platelet aggregation and thrombus subsequently. Thrombus will block artery coronaries.
., Carollina   +3 more
core  

Adiponectin diminishes platelet aggregation and sCD40L release. Potential role in the metabolic syndrome [PDF]

open access: yes, 2010
The proinflammatory and proatherogenic mediator, soluble CD40 ligand (CD40L), is increased in the metabolic syndrome (MS) and released from platelets. We hypothesized that adiponectin modulates platelet function, and we sought to evaluate the association
Colina, I. (Inmaculada)   +3 more
core   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Modulatory Efficiency of Vitamin C (Ascorbic Acid) on Collagen-Induced Platelet Aggregation and Dysfunction

open access: yesBiology, Medicine & Natural Product Chemistry
Platelet aggregation, coagulation, and activation are crucial for hemostasis. Collagen treatment can impair hemostatic processes leading to bleeding disorders like thrombosis; vitamin C may mitigate these effects.  Hence, modulatory efficiency of vitamin
Osah Martins Onwuka   +4 more
doaj   +1 more source

Evaluation of an automated light transmission aggregometry

open access: yesPlatelets, 2017
Light transmission aggregometry (LTA) is the “gold standard” for platelet function assessment, but it is time-consuming and labor intensive. Recently, an automated platelet aggregation method has been developed on a routine coagulation analyzer (Sysmex ...
Li-qin Ling   +7 more
doaj   +1 more source

PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis. [PDF]

open access: yesPLoS ONE, 2015
Sepsis severity has been positively correlated with platelet dysfunction, which may be due to elevations in nitric oxide (NO) and cGMP levels. Protein kinase C, Src kinases, PI3K and AKT modulate platelet activity in physiological conditions, but no ...
M Elisa Lopes-Pires   +5 more
doaj   +1 more source

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]

open access: yes, 2009
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian   +79 more
core   +2 more sources

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