Results 121 to 130 of about 222,697 (389)

Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]

open access: yes, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A   +5 more
core   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Geometrical Designs in Volumetric Bioprinting to Study Cellular Behaviors in Engineered Constructs

open access: yesAdvanced Healthcare Materials, EarlyView.
Curvature and spatial confinement guide cell behavior in volumetrically printed 3D constructs. Endothelial cells align and spread along specific geometries, while metastatic osteosarcoma cells proliferate independently of structural cues. Label‐free holographic microscopy captures real‐time, long‐term cell–material interactions, highlighting Gel‐PEG's ...
Julia Simińska‐Stanny   +3 more
wiley   +1 more source

CHANGES OF PLATELET HEMOSTASIS PARAMETERS IN PATIENTS WITH HYPERTENSION COMBINED COURSE OF COPD IN THE DYNAMICS OF HOSPITAL TREATMENT PERIOD

open access: yesUkrainian Scientific Medical Youth Journal, 2016
The combination of arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) is often encountered in clinical practice. To determine the state of functional activity of platelets in patients with AH in conjunction with COPD before and ...
S. O. Samoilova
doaj  

Fucosylated Glycosaminoglycan Oligosaccharide HS14, Derived from Sea Cucumbers, Is a Novel Inhibitor of Platelet Toll-like Receptor 2

open access: yesMarine Drugs
(1) Background: Toll-like receptor 2 (TLR2) on platelets is increasingly recognized as a pivotal mediator in infection-induced platelet activation and aggregation, contributing to both inflammatory and thrombotic diseases.
Huifang Sun   +8 more
doaj   +1 more source

Dasatinib inhibits coated-platelet generation in patients with chronic myeloid leukemia

open access: yesPlatelets, 2019
Since the introduction of tyrosine kinase inhibitors, the overall survival of patients with chronic myeloid leukemia has markedly improved. However long term use of these drugs results in various adverse events. Treatment with second generation dasatinib
Gabriella Mezei   +7 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Salivary Antigen-5/CAP Family Members Are Cu2+-dependent Antioxidant Enzymes That Scavenge O2⨪ and Inhibit Collagen-induced Platelet Aggregation and Neutrophil Oxidative Burst [PDF]

open access: hybrid, 2013
Teresa C. F. Assumpção   +9 more
openalex   +1 more source

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