Results 161 to 170 of about 237,328 (413)
Resumo Introdução Diante da alta incidência das doenças cardiovasculares, muitos são os pacientes que fazem uso de medicações para prevenção e tratamento dessas desordens.
Liciane dos Santos MENEZES+2 more
doaj +1 more source
Multiscale simulation of blood flow in brain arteries with an aneurysm [PDF]
Interfacing atomistic-based with continuum-based simulation codes is now required in many multiscale physical and biological systems. We present the first results from coupled atomistic-continuum simulations on 190,000 processors. Platelet aggregation in the patient-specific model of an aneurysm has been modeled using a high-order spectral/hp element ...
arxiv
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li+3 more
wiley +1 more source
The combination of arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) is often encountered in clinical practice. To determine the state of functional activity of platelets in patients with AH in conjunction with COPD before and ...
S. O. Samoilova
doaj
A natural binary electrolyte additive is designed to achieve an enhanced interfacial molecule adsorption layer for Zn protection via reshaping the electric double‐layer structure. Consequently, the hydrogen evolution reaction is suppressed and a robust inorganic solid electrolyte interphase is constructed for dendrite‐free Zn plating.
Kai Liu+14 more
wiley +1 more source
Dasatinib inhibits coated-platelet generation in patients with chronic myeloid leukemia
Since the introduction of tyrosine kinase inhibitors, the overall survival of patients with chronic myeloid leukemia has markedly improved. However long term use of these drugs results in various adverse events. Treatment with second generation dasatinib
Gabriella Mezei+7 more
doaj +1 more source
5′‐N‐ETHYLCARBOXAMIDOADENOSINE: A POTENT INHIBITOR OF HUMAN PLATELET AGGREGATION [PDF]
Noel J. Cusack, S.M.O. Hourani
openalex +1 more source
Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation [PDF]
The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations of PAF (5 nM) and A23187 (1 mM) was ...
Rasheed, Huma, Saeed, Sheikh Arshad
core +1 more source
Materials Advances in Devices for Heart Disease Interventions
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra+11 more
wiley +1 more source
Design of HIV-1-PR inhibitors which do not create resistance: blocking the folding of single monomers [PDF]
One of the main problems of drug design is that of optimizing the drug--target interaction. In the case in which the target is a viral protein displaying a high mutation rate, a second problem arises, namely the eventual development of resistance. We wish to suggest a scheme for the design of non--conventional drugs which do not face any of these ...
arxiv