Results 1 to 10 of about 175,124 (315)
Determination of Antibody Activity by Platelet Aggregation
Bio-Protocol, 2023 Platelets play an important role in hemostasis by forming clots and stopping bleeding. In immune thrombotic conditions, platelets and leukocytes are aberrantly activated by pathogenic antibodies resulting in platelet aggregates and NETosis, leading to ...
Halina Leung +3 more
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Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx [PDF]
Hematology, Transfusion and Cell TherapyBackground and Objectives: The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet refractoriness ...
Thiago Henrique Costa +2 more
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HUMAN NATURAL ANTIBODIES TO PORCINE PLATELETS
Transplantation, 1994 The specificity of human natural antibodies directed against blood cells from pigs was investigated by ELISA and immunoblotting. Both IgG and IgM were identified as xenoantibodies reacting with pig platelets adsorbed to microplates. The antibodies could be absorbed on platelets as well as on RBC, suggesting that the corresponding antigens are expressed
Ignacio Anegon +4 more
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Neonatal and fetal alloimmune thrombocytopenia [PDF]
Romanian Journal of Medical Practice, 2022 Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the result of maternal alloantibodies interaction with human platelets antigen. Maternal alloantibodies are generated following the contact of maternal immune system with paternally acquired ...
Ioana Emanuela Atanasescu +4 more
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Zhongguo shuxue zazhi, 2023 Objective To analyze the factors affecting the efficacy of platelet transfusion and the specificity of HLA-Ⅰ antibodies in tumor patients. Methods Tumer patients applied for platelet transfusion from November 2019 to July 2021 in Sichuan Cancer Hospital ...
Juan SAI, Shanshan WAN, Li TIAN
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Transfusion effect of 0.5-dose of apheresis platelet in pediatric patients
Zhongguo shuxue zazhi, 2023 Objective To investigate the transfusion effect of 0.5-dose of apheresis platelet in pediatric patients. Methods A total of 195 children who underwent 0.5-dose platelet transfusion from August 2021 to June 2022 were enrolled, and the platelet count ...
Lijuan QIU +3 more
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Platelet antibody of blood donors in Suzhou
Zhongguo shuxue zazhi, 2022 Objective To study the incidence and specificity of platelet antibody in blood donors in Suzhou, analyze the distribution characteristics of platelet antibody in blood donors in this area, and explore the significance of platelet antibody detection in ...
Li DONG +8 more
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Asian Journal of Transfusion Science, 2022 The application of flow cytometry (FC) is diverse and this powerful tool in used in multiple disciplines such as molecular biology, immunology, cancer biology, virology, and infectious disease screening.
Rajendra Chaudhary, Sudipta Sekhar Das
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Acta Obstetricia et Gynecologica Scandinavica, 2022 Introduction It is well known that HPA‐1a antibodies lead to fetal and neonatal alloimmune thrombocytopenia (FNAIT), and an association with reduced birthweight in boys has been reported. Although it remains unclear whether HLA antibodies cause FNAIT, an
Yang Xue +6 more
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Annals of Medicine, 2022 Objective The aim of the present study was to detect the association between platelet glycoprotein-specific autoantibodies and the patient response to short-term high-dose dexamethasone (HD-DXM) + prednisone maintenance treatment.
Yan-Qiu Hou +6 more
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