Results 11 to 20 of about 939,403 (293)

Platelet antibody of blood donors in Suzhou

open access: yesZhongguo shuxue zazhi, 2022
Objective To study the incidence and specificity of platelet antibody in blood donors in Suzhou, analyze the distribution characteristics of platelet antibody in blood donors in this area, and explore the significance of platelet antibody detection in ...
Li DONG   +8 more
doaj   +2 more sources

Platelet antibody production in children with congenital heart disease leading to coagulation dysfunction and reduced platelet function

open access: yesZhongguo shuxue zazhi
[Objective] To analyze the production of platelet antibodies in children with congenital heart disease, identify the types of antibodies, and explore their effects on platelet count, coagulation function and platelet function.
ZHEN Zida   +4 more
doaj   +2 more sources

Streptococcus oralis induces platelet aggregation through coordinated GPIbα and FcγRIIA signalling [PDF]

open access: yesPlatelets
Background Streptococcus oralis is the most prevalent viridans group streptococcus associated with infective endocarditis (IE), yet the platelet activation mechanisms that underpin its pathogenicity remain poorly defined.
Rachel Lamerton   +4 more
doaj   +2 more sources

Antibody identification and analysis of 80 children with positive platelet antibody in initial screening

open access: yesZhongguo shuxue zazhi
Objective To explore the distribution and types of platelet antibodies in children with positive platelet antibody in initial screening. Methods Blood samples of 80 pediatric patients who applied for platelet transfusion in our hospital from September ...
Xiaohuan WANG   +4 more
doaj   +2 more sources

Progress and Development of Platelet Antibody Detection [PDF]

open access: yesTransfusion and Apheresis Science, 2020
Human platelet antibody (HPA) detection is necessary for the diagnosis and therapeutic decisions for refractoriness to platelet transfusions, post transfusion purpura and fetal and neonatal alloimmune thrombocytopenia. In the last four to five decades many new developments, both in knowledge and methods, have increased the quality of platelet serology.
Masja de Haas
exaly   +3 more sources

HLA class I antibody distribution and cross-matching strategies in immune platelet transfusion refractory patients: a retrospective cohort study [PDF]

open access: yesFrontiers in Medicine
BackgroundThis study aimed to investigate the distribution characteristics and clinical significance of human leukocyte antigen class I antibodies in patients with immune-mediated platelet transfusion refractoriness (PTR) in this region, and to evaluate ...
Yu Zou   +4 more
doaj   +2 more sources

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

open access: yes, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S.   +3 more
core   +8 more sources

Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia [PDF]

open access: yesFrontiers in Immunology
BackgroundIn fetal and neonatal alloimmune thrombocytopenia (FNAIT), maternal antibodies react with alloantigen expressed on fetal platelets, leading to their clearance via antibody-dependent phagocytosis.
Xiuzhang Xu   +14 more
doaj   +2 more sources

Neonatal and fetal alloimmune thrombocytopenia [PDF]

open access: yesRomanian Journal of Medical Practice, 2022
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the result of maternal alloantibodies interaction with human platelets antigen. Maternal alloantibodies are generated following the contact of maternal immune system with paternally acquired ...
Ioana Emanuela Atanasescu   +4 more
doaj   +1 more source

Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness

open access: yesHematology
Objectives: HLA Class I, HPA (Human platelet antigen), CD36 allo/isoantibodies, and platelet glycoprotein autoantibodies are the primary causes of immune-mediated platelet transfusion refractoriness (iPTR).
Bing Zhang   +7 more
doaj   +2 more sources

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