Results 231 to 240 of about 175,124 (315)

CD63 Immunological Activation Versus Hemostatic Function: Platelet Alterations After Polytrauma. [PDF]

Curr Issues Mol Biol
Roemmermann G, Bohe O, Heimann L, Wirth F, Drumm F, Biberthaler P, Moog P, Schwenk C, Muehlhaupt N, Wan L, Hanschen M.   +10 more
europepmc   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

Advanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu, Mengxi Xiu, Shijun Yu, Zhiqin Chen, Yandong Li, Yong Gao   +5 more
wiley   +1 more source

Clinical characteristics of patients with acute pulmonary embolism complicated with antiphospholipid syndrome: a case control study. [PDF]

BMC Pulm Med
Wan J, Xu S, Yang J, Liu Q, Yang R, Kang W, Yang J, Xing X.   +7 more
europepmc   +1 more source

Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis

Advanced Science, EarlyView.
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang, Yibin Jia, Zhikai Li, Yunhong Zhang, Chao Wang, Yanbo Liang, Jiaoyan Qiu, Mingyuan Sun, Xiaoshuang Chen, Miao Huang, Yu Zhang, Jianbo Wang, Hong Liu, Chuanbin Mao, Lin Han   +14 more
wiley   +1 more source

Afucosylated IgG Promote Thrombosis in Mouse Injected with SARS-CoV-2 Spike Expressing Megakaryocytes. [PDF]

Int J Mol Sci
Mabrouk M, Atifi F, Wahnou H, Allaoui A, Zaid N, Naya A, Agbani EO, Khalki L, Khyatti M, Tijani Y, Akarid K, Arnoult D, Abou-Saleh H, El Faqer O, Labied S, Ammara M, Guessous F, Jalali F, Zaid Y.   +18 more
europepmc   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

A Microfluidic Blood Vessel-On-Chip Model of Thrombosis

Jansson-Edqvist J, Mencarini T, Peghaire C, Dibble M, Ahnstroem J, Pericleous C, Redaelli A, van Batenburg-Sherwood J, Randi AM.   +8 more
europepmc   +1 more source

Transmembrane thiol isomerase TMX1 inhibits fibrin formation by down-regulation of platelet phosphatidylserine exposure. [PDF]

Cell Commun Signal
Zhao Z, Zhang Y, Cheng Y, Chen X, Lu Y, Han Y, Wu Y, Yang A.   +7 more
europepmc   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, EarlyView.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

Effect of phosphodiesterase inhibitors on platelet function. [PDF]

Biochem Biophys Rep
Hochuli R, Dicenta V, Laspa Z, Sigle M, Harm T, Castor T, Rohlfing AK, Gawaz MP.   +7 more
europepmc   +1 more source