Results 251 to 260 of about 2,103,612 (328)

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura. [PDF]

Front Immunol
Yokota Y, Hara M, Nakajima H.
europepmc   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients [PDF]

, 2018
Adelman, Avril, et al,, Schechtman, Kenneth B, Spinella, Philip C   +3 more
core   +1 more source

Extravascular coagulation regulates haemostasis independently of activated platelet surfaces in an in vivo mouse model. [PDF]

Commun Biol
Sakata A, Tatsumi K, Matsumoto N, Mackman N, Harada S, Kawasaki R, Okuyama-Nishida Y, Soeda T, Nogami K, Shima M.   +9 more
europepmc   +1 more source

Aminated graphene nanosheet stimulates the maturation of hiPSCs‐derived cardiomyocytes in vitro and enhances their survival in vivo

BMEMat, EarlyView.
Aminated graphene (G‐NH2) niche matrix plays a pivotal role in precisely manipulating cardiac differentiation and maturation of hiPSCs. The molecular mechanism underlying cardiomyocyte maturation is closely linked to the PDGF‐β signaling pathway. Cardiomyocytes derived from the G‐NH2 matrix exhibit enhanced activity and functionality in vivo.
Yin Xu, Xvdong Wang, Zihao Wang, Qi Chen, Donghui Zhang, Nianguo Dong, Jianglin Wang   +6 more
wiley   +1 more source

Engraftment outcome of patients with anti-HLA antibodies in HLA-mismatched peripheral blood stem cell transplantation. [PDF]

Int J Hematol
Hagino T, Ikegame K, Tanaka H, Kanda Y, Kaida K, Fukuda T, Kondo Y, Sato M, Doki N, Nakamae H, Matsuoka KI, Mori Y, Sano H, Eto T, Kawakita T, Hashii Y, Ichinohe T, Atsuta Y, Kanda J, HLA Working Group of Japanese Society for Transplantation, Cellular Therapy.   +20 more
europepmc   +1 more source

Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody. [PDF]

Sci Rep
Zhai Z, Guo Y, Yu L, Wang Y, Wang L, Li Q, Yuan Y, Tang L.   +7 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Early caplacizumab and obinutuzumab enable successful treatment of relapsing thrombotic thrombocytopenic purpura without therapeutic plasma exchange: a case report. [PDF]

Front Immunol
Schimpf J, Haller P, Zitt E.
europepmc   +1 more source