Results 261 to 270 of about 2,173,038 (398)

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

The Evaluation of ABO Antibody Titers and Effect of Physical and Lifestyle Factors in Single Donor Platelets From O Blood Group Donors: A Cross-Sectional Study. [PDF]

Cureus
Thakur R, Pawde Y, Mujhalda B, Yadav A, Walling I.   +4 more
europepmc   +1 more source

The antagonism of platelet-activating factor and hyperacute organ rejection [PDF]

, 1990
Banner, B, Chapman, F, Makowka, L, Mazzaferro, V, Pascualone, A, Podesta, L, Qian, S, Saunders, R, Sher, L, Sico, E, Starzl, TE, Sun, H, Zerbe, TR   +12 more
core  

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Functional toll-like receptor 4 links endotoxin sensing to platelet priming in feline platelets. [PDF]

Front Vet Sci
Li RHL, Shaverdian M, Chen C, Stuhlmann C, Stern JA, Nguyen N.   +5 more
europepmc   +1 more source

Coagulation abnormalities in Ehrlichia canis-infected dogs and detection and dynamics of anti-platelet antibodies in thrombocytopenic dogs

, 2018
Sarah Shropshire, Lappin, Michael, Dow, Steve, Olver, Christine, Webb, Craig, Ames, Marisa   +5 more
openalex   +2 more sources

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

Lauryl gallate promotes platelet activation and thrombus formation: a promising application to stop bleeding. [PDF]

Clin Sci (Lond)
Hadjkacem B, Garcia C, Series J, Pons V, Mahmoudi A, Gales C, Voisin S, Ribes A, Gratacap MP, Gargouri A, Payrastre B.   +10 more
europepmc   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

TLR2-induced surface mobilization and release of CD14 in human platelets. [PDF]

Sci Rep
Kobsar A, Vaz DS, Zeller-Hahn J, Koessler A, Weber K, Kuhn S, Stigloher C, Koessler J.   +7 more
europepmc   +1 more source