Results 41 to 50 of about 2,103,612 (328)
Horse mares carrying mule foals were immunized during the last trimester of pregnancy with whole acid-citrate-dextrose-anticoagulated donkey blood to experimentally induce neonatal alloimmune thrombocytopenia.
S. Ramirez+3 more
semanticscholar +1 more source
Two monoclonal anti-platelet antibodies, 3B2 and 8G11, have been raised that are specific for normal human platelets. 3B2 is unique in that it has decreased reactivity for platelets from 16 patients with autoimmune thrombocytopenic purpura [mean platelet
D. Varon, S. Karpatkin
semanticscholar +1 more source
Platelet destruction in immune thrombocytopenia is caused by autoreactive antibody and T-cell responses, most commonly directed against platelet glycoprotein IIb/IIIa.
Lindsay S. Hall+5 more
doaj +1 more source
When Two are Better than One: Modeling the Mechanisms of Antibody Mixtures [PDF]
It is difficult to predict how antibodies will behave when mixed together, even after each has been independently characterized. Here, we present a statistical mechanical model for the activity of antibody mixtures that accounts for whether pairs of antibodies bind to distinct or overlapping epitopes.
arxiv +1 more source
[Objective] To analyze the production of platelet antibodies in children with congenital heart disease, identify the types of antibodies, and explore their effects on platelet count, coagulation function and platelet function.
ZHEN Zida+4 more
doaj +1 more source
In a high‐risk patient with subacute heparin‐induced thrombocytopenia (HIT) type A (platelet count recovery following acute HIT but with persisting platelet‐activating antibodies), in whom urgent cardiac surgery was required, a key clinical question ...
Andreas Koster+5 more
doaj +1 more source
In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism. [PDF]
We sought to determine a role for platelets in in vivo angiogenesis, quantified by changes in the capillary to fibre ratio (C:F) of mouse skeletal muscle, utilising two distinct forms of capillary growth to identify differential effects.
Ian M Packham+3 more
doaj +1 more source
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Re-Evaluation Of Modified Rapid Monoclonal Antibody Immobilization Of Platelet Antigen (MR-MAIPA) For Detecting Platelet Antibody In Patients With Suspected Immune Thrombocytopenia [PDF]
Ujian antibodi terhadap platelet di Malaysia hanya dijalankan di Pusat Darah Negara (PDN), Kuala Lumpur. Sebelum tahun 2013, ujian antibodi terhadap platelet di Malaysia dijalankan menggunakan teknik MAIPA. Namun begitu, MAIPA memerlukan masa selama tiga
Aziz, Mohd Fahmi
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