Results 81 to 90 of about 175,124 (315)

Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis

Platelets, 2017
GluN1 is a mandatory component of N-methyl-D-aspartate receptors (NMDARs) best known for their roles in the brain, but with increasing evidence for relevance in peripheral tissues, including platelets.
Taryn N. Green, Justin R. Hamilton, Marie-Christine Morel-Kopp, Zhaohua Zheng, Ting-Yu T. Chen, James I. Hearn, Peng P. Sun, Jack U. Flanagan, Deborah Young, P. Alan Barber, Matthew J. During, Christopher M. Ward, Maggie L. Kalev-Zylinska   +12 more
doaj   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Investigation of the correlation between platelet antibodies and peripheral blood cytopenia in patients with hepatocellular carcinoma

Scientific Reports
The primary triggers that stimulate the body to generate platelet antibodies via immune mechanisms encompass events such as pregnancy, transplantation, and blood transfusion.
Rui Han, Hui-Chan He, Wan-Ning Zhang, Ze-Tao Pan, Chen-Yang Feng, Ming-Jian Liang, Mei-Yi Wu, Wei Zhong, Wen-Qian Lin   +8 more
doaj   +1 more source

Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury. [PDF]

, 1975
Margaret J. Polley, Ralph L. Nachman
openalex   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

Effect of anti-P1A1 antibody on human platelets. I. The role of complement [PDF]

, 1979
DB Cines, AD Schreiber
openalex   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

Advanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng, Xuemei Zhong, Lu Deng, Xinling He, Miaoxizi Luo, Ruibing Wang, Jinming Zhang   +6 more
wiley   +1 more source

Caracterização da ativação plaquetária nos concentrados de plaquetas por citometria de fluxo

Revista Brasileira de Hematologia e Hemoterapia, 2003
Flow cytometric characterization of platelet membrane glycoproteins expression and procoagulant surface is a sensitive technique to identify platelet activation in platelet concentrates.
Landi Evaldo P., Marques Júnior José F. C.   +1 more
doaj  

Detection of platelet antibodies by monoclonal antibody immobilization of platelet antigens (MAIPA) assay

, 2012
published_or_final_version ; Medical Sciences ; Master ; Master of Medical ...
openaire   +3 more sources

Immune hemolytic anemia and thrombocytopenia secondary to quinidine: in vitro studies of the quinidine-dependent red cell and platelet antibodies [PDF]

, 1979
Zella R. Zeigler, RK Shadduck, Alan Winkelstein, TK Stroupe   +3 more
openalex   +1 more source