Background Chronic liver disease (CLD) is often complicated by severe thrombocytopenia (platelet count 50,000/µL at baseline: the proportions of patients who did not require platelet transfusion were 84–96%, which might be overestimated.
Hiroaki Nomoto+11 more
doaj +1 more source
Platelet variables in community-acquired pneumonia in children with respiratory infections
Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods.
E. A. Kozyrev+4 more
doaj +1 more source
Dose- and time-related platelet response with apheresis platelet concentrates and pooled platelets [PDF]
This study was carried out to compare the post-transfusion platelet increment between the apheresis platelet concentrate (n=74) and pooled platelets (n=54).
Khan, Lutfunnahar+2 more
core +7 more sources
Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]
Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv +1 more source
Reticulocyte Count and Platelet Count as Predictors of Morphological Remission/Hemopoitic Recovery in Acute Lymphoblastic Leukemia (ALL) after Induction Chemotherapy [PDF]
Objectives: To determine the predictive values of reticulocyte and platelet count for remission in cases of acute lymphoblastic leukemia after induction therapy.
Huma Riaz, Hamzullah Khan, Shahtaj Khan, Sadaf Chiragh,
core +6 more sources
Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
Platelet function tests (PFTs) before cardiac surgery are predictive of postoperative bleeding and can guide a correct timing of surgery in patients under P2Y12 inhibitors. Thrombocytopenia affects PFT and may determine postoperative bleeding.
Marco Ranucci, Ekaterina Baryshnikova
doaj +1 more source
HEPATIC DYSFUNCTION IN DENGUE: A TERITARY CARE HOSPITAL EXPERINCE [PDF]
Objective: The objective of the study was to evaluate liver dysfunction in patients with dengue infections and corelation between liver function test and platelet count. Methods: Hospital-based case−control study conducted on 141 hospitalized with Dengue
CHOUHAN, PRATIMA+3 more
core +1 more source
Pre-eclampsia and platelet indices: a cross sectional study [PDF]
Background: Pre-eclampsia is a complex disease process originating at the maternal- fetal interface that affects multiple organ systems. The exact pathophysiology of preeclampsia is not known but it is considered to be associated with endothelial cell ...
Ashraf, Aadil+3 more
core +2 more sources
Assessing the periprocedural magnitude of platelet count change in response to lusutrombopag
Background & Aims: Despite limitations, platelet transfusion has been used to minimise bleeding risk in patients with thrombocytopaenia. Lusutrombopag is an oral, thrombopoietin receptor agonist approved for treatment of thrombocytopaenia associated ...
Robert S. Brown, Jr.+7 more
doaj