Results 51 to 60 of about 399,591 (306)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Associations of Platelet Count with Inflammation and Response to Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis

open access: yesFrontiers in Pharmacology, 2020
Background: Increased platelet count has been reported in ankylosing spondylitis (AS) patients, but its clinical significance is still largely elusive.
Hongyan Qian   +11 more
doaj   +1 more source

Trends in platelet count among cancer patients

open access: yesExperimental Hematology & Oncology, 2022
An elevated platelet count has been associated with an increased incidence of cancer and poor survival for many cancer types. In this study, platelet levels were captured among cancer patients in the 2 years prior to and following a cancer diagnosis.
Vasily Giannakeas
doaj   +1 more source

Penatalaksanaan Prabedah Penderita Dengan Trombositopenia [PDF]

open access: yes, 2009
Bleeding, either medical or surgical bleeding, remains an important issue in surgery. Therefore, complete blood count and bleeding time are routinely checked in patients undergoing surgical procedures.
Vera, V. (Vera)
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Pathophysiological aspects of Platelet-Mediated Thrombosis and Bleeding in Essential Thrombocythemia: [PDF]

open access: yes, 1998
Thrombocytosis, i.e. an elevation of the platelet count, is a common finding in clinical practice. In general, patients with thrombocytosis are distinguished into two main categories, primarily based on the cause underlying the increased platelet count ...
Genderen, P.J.J. (Perry) van
core   +1 more source

Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]

open access: yes, 2017
NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina   +8 more
core   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Evaluation of burn sepsis with reference to platelet count as a prognostic indicator

open access: yesCHRISMED Journal of Health and Research, 2020
Background: Burn is the oldest form of injury to inflict humankind, and infection is a major challenge in the management of burn patients and is a leading cause of morbidity and mortality.
Surya Prakash   +2 more
doaj   +1 more source

Mean Platelet Volume and the Ratio of Mean Platelet Volume/Platelet Count in Acute Rheumatic Fever

open access: yesJournal of Pediatric Research, 2021
Aim:Acute rheumatic fever (ARF) is an endemic disease especially in developing countries. Due to an autoimmune response to group B streptococcus throat infection, ARF develops in susceptible children. Mean platelet volume (MPV) reflects the platelet size
Dolunay Gürses   +2 more
doaj   +1 more source

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