Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]
, 1994 Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O. +6 more
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Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
Advanced Science, EarlyView.This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu +15 more
wiley +1 more source
Serum level of lactate dehydrogenase, homocystein, hemoglobin and platelet in preeclampsia [PDF]
, 2011 Objectives: Pre-eclampsia affects approximately 5-8% of pregnant women. The aim of this study was to compare the serum level of Lactate dehydrogenase (LDH), Homocystein, Hemoglubin and platelet in pregnant women diagnosed as pre-eclampsia and a normal ...
Azarhoosh, R. +5 more
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Germline copy number variants in RUNX1: An updated case report and a decade-old red herring
BJC ReportsPathogenic/likely pathogenic (P/LP) germline variants in RUNX1 cause familial platelet disorder with associated myeloid malignancies (FPDMM), also known as RUNX1-Familial Platelet Disorder (RUNX1-FPD, or FPD), a condition characterized by qualitative and
Natalie T. Deuitch +9 more
doaj +1 more source
Advanced Science, EarlyView.SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui +15 more
wiley +1 more source
Obliterative bronchiolitis after lung transplantation: a fibroproliferative disorder associated with platelet-derived growth factor. [PDF]
, 1992 Marshall I. Hertz +9 more
openalex +1 more source
Decreased mean platelet volume in panic disorder
Neuropsychiatric Disease and Treatment, 2014 Işil Göğçegöz Gül, Gül Eryilmaz, Eylem Özten, Gökben Hizli Sayar Neuropsychiatry Health, Practice, and Research Center, Uskudar University, Istanbul, Turkey Aim: The relationship between psychological stress ...
Göğçegöz Gül I +3 more
doaj
Advanced Science, EarlyView.This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang +4 more
wiley +1 more source
Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies. [PDF]
Leukemia, 2021 Decker M +13 more
europepmc +1 more source
MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]
, 2008 Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
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