Journal of Immunology, 1996 Polymorphonuclear leukocytes have been shown to play an important role in myocardial ischemia (MI) and reperfusion (R) injury. Since blockade of platelet-endothelial cell adhesion molecules (PECAM-1) inhibits neutrophil transmigration in vitro and in ...
Toyoaki Murohara +3 more
semanticscholar +1 more source
Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in mice [PDF]
, 2009 Background: Pancreatic infiltration by leucocytes represents a hallmark in acute pancreatitis. Although leucocytes play an active role in the pathophysiology of this disease, the relation between leucocyte activation, microvascular injury and haemorrhage
Deduchovas, O. +8 more
core +1 more source
Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration
Advanced Materials Technologies, EarlyView.This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley +1 more source
Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function. [PDF]
Arterioscler Thromb Vasc Biol, 2022 Liao D +6 more
europepmc +1 more source
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Advanced Materials Technologies, EarlyView.Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
Targeting the tumor microenvironment in colorectal peritoneal metastases
, 2020 Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim +4 more
core +1 more source
The role of tumor necrosis factor-α and interferon-γ in the hyperglycemia-induced ubiquitination and loss of platelet endothelial cell adhesion molecule-1 in rat retinal endothelial cells. [PDF]
Microcirculation, 2021 Eshaq RS, Harris NR.
europepmc +1 more source
Platelet/Endothelial Cell Adhesion Molecule-1(PECAM-1, CD31): The All-Purpose Adhesion Molecule.
Trends in Glycoscience and Glycotechnology, 1994 血小板/内皮細胞接着分子-1 (PECAM-1、CD31、以後ここでは“PECAM”と表すことにする) は、免疫グロブリンスーパーファミリーに属する130kDaの糖タンパク質である。この糖タンパク質は、血管内皮細胞間の接着部位に集積し、また血小板や末梢に存在する白血球の細胞表面には分散して存在している。また、骨髄や循環系に関係する多くの細胞に発現し、数種の細胞接着反応を仲介することができる。内皮細胞結合のような同じ細胞同士の接着 (同種細胞間接着) 及び内皮細胞への白血球の結合のような異なる細胞間の接着 (異種細胞間接着) に関わっている。分子レベルでは、PECAMは、同一分子同士でも結合 (PECAMとPECAMの結合) し、また ...
openaire +2 more sources
Hyperglycemia-induced ubiquitination and degradation of β-catenin with the loss of platelet endothelial cell adhesion molecule-1 in retinal endothelial cells. [PDF]
Microcirculation, 2020 Eshaq RS, Harris NR.
europepmc +1 more source
Soluble platelet endothelial cell adhesion molecule 1 (sPECAM-1) improves diagnostic accuracy of D-Dimer in patients with suspected deep vein thrombosis (DVT). [PDF]
J Thromb Thrombolysis, 2020 Kellermair J +7 more
europepmc +1 more source