Results 101 to 110 of about 1,059,321 (361)
Platelet Function tests: A Comparative Review [PDF]
In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet defects promote bleeding, whereas the high residual reactivity of
Abbate, Rosanna+3 more
core +1 more source
Platelet function in sepsis [PDF]
Coagulation abnormalities and thrombocytopenia are common in severe sepsis, but sepsis-related alterations in platelet function are ill-defined.The purpose of this study was to elucidate the effect of sepsis on platelet aggregation, adhesiveness, and growth factor release.Agonist-induced platelet aggregation was measured in platelet-rich plasma ...
Yaguchi, ARINO+3 more
openaire +3 more sources
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Density-Functional Theory Study of Hydrogen Induced Platelets (HIPs) in Silicon [PDF]
In this contribution we present the results of Density-Functional Theory (DFT) calculations of platelets as modelled by infinite planar arrangements of hydrogen atoms and vacancies in (100) planes of silicon. From the observation of the relaxed platelet structures and the comparison of their energy with the one of hydrogen molecules dissolved in ...
arxiv +1 more source
Platelet Inventory Management with Approximate Dynamic Programming [PDF]
We study a stochastic perishable inventory control problem with endogenous (decision-dependent) uncertainty in shelf-life of units. Our primary motivation is determining ordering policies for blood platelets. Determining optimal ordering quantities is a challenging task due to the short maximum shelf-life of platelets (3-5 days after testing) and high ...
arxiv
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda+15 more
wiley +1 more source
Effect of propranolol on platelet function [PDF]
B B Weksler, M Gillick, J Pink
openalex +3 more sources
Phase behaviour of binary mixtures of diamagnetic colloidal platelets in an external magnetic field [PDF]
Using fundamental measure density functional theory we investigate paranematic-nematic and nematic-nematic phase coexistence in binary mixtures of circular platelets with vanishing thicknesses. An external magnetic field induces uniaxial alignment and acts on the platelets with a strength that is taken to scale with the platelet area.
arxiv +1 more source