Results 31 to 40 of about 1,059,321 (361)

Platelet responses to agonists in a cohort of highly characterised platelet donors are consistent over time. [PDF]

, 2016
BACKGROUND AND OBJECTIVES: Platelet function shows significant inheritance that is at least partially genetically controlled. There is also evidence that the platelet response is stable over time, but there are few studies that have assessed consistency ...
Attwood, A., Cardigan, R., Furnell, A., Garner, S. F., Goodall, A. H., Harrison, P., Jones, Chris I., Kahan, B. C., Kelly, A. M., Ouwehand, W. H.   +9 more
core   +3 more sources

Platelet Function and Valproate

Pediatric Neurology Briefs, 1999
The role of arachidonate metabolites in valproate-induced platelet dysfunction and hemorrhagic diathesis was investigated by ex vivo methods at the Albert Szent-Gyorgyi Medical University, Szeged, Hungary.
J Gordon Millichap
doaj   +1 more source

Platelet count and function in umbilical cord blood versus peripheral blood in term neonates

Platelets, 2021
Platelet function in neonates is sparsely investigated. The majority of previous studies investigated platelets in umbilical cord (UC) blood rather than in peripheral blood. We included 20 term neonates and sampled UC blood and peripheral blood within 20 
Alexander K. Grevsen, Claus V. B. Hviid, Anne K. Hansen, Anne-Mette Hvas   +3 more
doaj   +1 more source

Expression of ADP receptor P2Y12, thromboxane A2 receptor and C-type lectin-like receptor 2 in cord blood-derived megakaryopoiesis

Platelets, 2021
The ADP receptor P2Y12, the thromboxane A2 receptor (TXA2R) and the C-type lectin-like receptor 2 (CLEC-2) mediate platelet activation by different mechanisms. Only little is known about the expression of the receptors in human megakaryopoiesis.
Catharina Gerhards, Stefanie Uhlig, Mani Etemad, Foteini Christodoulou, Karen Bieback, Harald Klüter, Peter Bugert   +6 more
doaj   +1 more source

Whole blood flow cytometry protocol for the assessment of platelet phenotype, function, and cellular interactions

Platelets, 2021
Platelets are a key component of the hemostatic system and their roles in inflammation via interactions with leukocytes have also gained attention in recent years.
Hui Ping Yaw, Suelyn Van Den Helm, Matthew Linden, Paul Monagle, Vera Ignjatovic   +4 more
doaj   +1 more source

Rare missense variants in Tropomyosin-4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects and excessive bleeding [PDF]

, 2021
BackgroundA significant challenge is faced for the genetic diagnosis of inherited platelet disorders where candidate genetic variants can be found in over 100 Bleeding, Thrombotic and Platelet disorder genes, especially within families where there is ...
, Bignell, Patricia, Fratter, Carl, Khan, Abdullah, Lester, Will, Lowe, Gillian, Morgan, Neil, Poulter, Natalie, Smith, Christopher, Stapley, Rachel   +9 more
core   +1 more source

Ontogeny of platelet function [PDF]

Blood Advances, 2019
AbstractAlthough the hemostatic potential of adult platelets has been investigated extensively, regulation of platelet function during fetal life is less clear. Recent studies have provided increasing evidence for a developmental control of platelet function during fetal ontogeny.
Andreas Margraf, Claudia Nussbaum, Markus Sperandio   +2 more
openaire   +3 more sources

Relation of Level of Platelet Inhibition after Eptifibatide with Major Cardiovascular Events in ST-Segment Elevation Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Majalah Kardiologi Indonesia, 2015
Background: Eptifibatide, an inhibitor of glycoprotein IIb/IIIa administered as adjunctive therapy to reperfusion therapy Primary PCI in STEMI patients.
Elisa Feriyanti Pakpahan, Sunarya Soerianata, Nur Haryono   +2 more
doaj   +1 more source

Identification of a pathogenic TUBB1 variant in a Chinese family with congenital macrothrombocytopenia through whole genome sequencing

Platelets, 2021
Congenital macrothrombocytopenia is a genetically heterogeneous group of rare disorders. We herein report a large Chinese family presented with phenotypic variability involving thrombocytopenia and/or giant platelets. Whole genome sequencing (WGS) of the
Yu Hou, Linlin Shao, Hai Zhou, Yanfeng Liu, Dianna G. Fisk, Elizabeth Spiteri, James L. Zehnder, Jun Peng, Bing M. Zhang, Ming Hou   +9 more
doaj   +1 more source

Bulk and interfacial properties of binary hard-platelet fluids [PDF]

Phys. Rev. E 69, 021506 (2004), 2003
Interfaces between demixed fluid phases of binary mixtures of hard platelets are investigated using density-functional theory. The corresponding excess free energy functional is calculated within a fundamental measure theory adapted to the Zwanzig model, in which the orientations of the particles of rectangular shape are restricted to three orthogonal ...
arxiv   +1 more source