Results 61 to 70 of about 1,059,321 (361)

Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]

, 1998
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Alloatti, Altieri, Bünger, Capron, Chang, Coker, Conforti, Cook, D'Souza, Dauber, Dreyer, Gilbert, Goulielmos, Grover, Hicks, Hoshiga, Kowalski, Kupatt, Languino, Mannaionini, Mogford, Möbert, Rodgers, Rousseau, Rubboli, Rösen, Sheppeck, Sheridan, Sixma, Swerlick, Takiguchi, Wheatley, Yang, Yang, Yang, Zahler   +35 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Evaluation of platelet activation parameters as quality markers for the stored platelets [PDF]

Journal of Medical Biochemistry, 2007
In order to investigate the potential use of platelets activation parameters as routine quality control indicators during liquid storage, 27 PC-BC units were kept at 22 oC for up to 5 days.
Subota Vesna, Vučetić Dušan, Balint Bela, Mijušković Zoran, Vojvodić Danilo, Pejović Janko, Mandić-Radić Slavka   +6 more
doaj  

Sex Differences in Midterm Prognostic Implications of High Platelet Reactivity After Percutaneous Coronary Intervention With Drug‐Eluting Stents in East Asian Patients: Results From the PTRG‐DES (Platelet Function and Genotype‐Related Long‐Term Prognosis in Drug‐Eluting Stent–Treated Patients With Coronary Artery Disease) Consortium

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Although high platelet reactivity (HPR) on clopidogrel is associated with higher ischemic events and lower bleeding events in patients who have undergone percutaneous coronary intervention with drug‐eluting stents, the differential risk of HPR
Soo‐Jin Kim, Ae‐Young Her, Young‐Hoon Jeong, Byeong‐Keuk Kim, Hyung Joon Joo, Yongwhi Park, Kiyuk Chang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Sang Yeub Lee, Jung Rae Cho, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin   +15 more
doaj   +1 more source

Density functional theory for colloidal mixtures of hard platelets, rods, and spheres [PDF]

, 2005
A geometry-based density functional theory is presented for mixtures of hard spheres, hard needles and hard platelets; both the needles and the platelets are taken to be of vanishing thickness. Geometrical weight functions that are characteristic for each species are given and it is shown how convolutions of pairs of weight functions recover each Mayer
arxiv   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Non-Linear Poisson-Boltzmann Theory of a Wigner-Seitz Model for Swollen Clays [PDF]

Phys. Rev. E 61, 1634 (2000)., 1999
Swollen stacks of finite-size disc-like Laponite clay platelets are investigated within a Wigner-Seitz cell model. Each cell is a cylinder containing a coaxial platelet at its centre, together with an overall charge-neutral distribution of microscopic co and counterions, within a primitive model description.
arxiv   +1 more source

Innovation and standardization of near-patient platelet function assays [PDF]

, 2020
This thesis focuses on innovation and standardization of platelet function assays in order to optimize patient diagnosis and treatment with respect to haemostasis (a process to prevent and stop bleeding).
Sang, Yaqiu
core   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

How does measurement of platelet P-selectin compare with other methods of measuring platelet function as a means of determining the effectiveness of antiplatelet therapy?

Platelets, 2019
Measurement of P-selectin on activated platelets as a means of measuring platelet function utilizing the technology described here has the advantage of not requiring immediate access to specialist equipment and expertise.
Susan C. Fox, Jane A. May, Natalia Dovlatova, Jackie R. Glenn, Andrew Johnson, Ann E. White, Ashwin Radhakrishnan, Stan Heptinstall   +7 more
doaj   +1 more source