Results 251 to 260 of about 160,648 (299)
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Standardization of platelet function tests

American Journal of Hematology, 1981
AbstractMethods for the standardization of several currently used platelet function tests (bleeding time, capillary fragility, platelet retention, platelet aggregation, platelet factor 3, and platelet volume profiles) are presented. Different variables that may interfere with the reproducibility of the results of each assay were identified and ...
P R, Roper-Drewinko   +5 more
openaire   +2 more sources

A new platelet function test

Thrombosis Research, 1990
A method for screening EDTA(K3) blood samples for platelet function is described. The general availability of whole blood platelet counters in the clinical laboratory suggested their use to measure platelet aggregation. To simplify the collection and storage of blood samples, a method utilizing EDTA collected blood is described. Addition of calcium and
W L, Ryan, K, Hakenkamp, E, Sullivan
openaire   +2 more sources

Platelet Function Tests in Disease

Annual Review of Medicine, 1973
Abnormal platelet function may result from congenital or acquired disturbances in the platelets themselves or their plasma milieu in patients with hemorrhage or thrombosis. Although standardization is difficult and results overlap between patient groups certain tests are abnormal in patients with diabetes and atherosclorosis and in women on oral ...
T B, Tschopp, M B, Zucker
openaire   +2 more sources

Platelet Function Testing: Quality Assurance

Seminars in Thrombosis and Hemostasis, 2007
Platelet function tests are widely used for the diagnosis of platelet disorders. In recent years there has been increasing interest in the use of platelet function tests to monitor antiplatelet drug therapy. Quality assurance is important to optimize the performance of laboratory assays but it has not been widely applied to platelet function tests ...
Catherine P M, Hayward, John, Eikelboom
openaire   +2 more sources

Platelet Function Testing in Atherothrombotic Disease

Current Pharmaceutical Design, 2012
Platelet function testing was introduced more than a century ago with the invention of bleeding time; a test which has now been replaced by more accurate methods. Light transmittance aggregometry is traditionally regarded as the gold standard for evaluating platelet function.
Grove, Erik Lerkevang   +2 more
openaire   +3 more sources

Platelet function inhibitors and platelet function testing in neurointerventional procedures

Journal of NeuroInterventional Surgery, 2014
Over the past decade there has been a growing use of intracranial stents for the treatment of both ischemic and hemorrhagic cerebrovascular disease, including stents to assist in the remodeling of the neck of aneurysms as well as the use of flow diverting devices for aneurysm treatment.
Chirag D, Gandhi   +25 more
openaire   +2 more sources

Whole Blood Platelet Aggregometry and Platelet Function Testing

Seminars in Thrombosis and Hemostasis, 2009
Platelet aggregometry has been the reference method employed to detect, diagnose, and monitor qualitative platelet disorders since the early 1960s. Lumiaggregometry and impedance-based whole blood lumiaggregometry have advantages over light transmittance aggregometry in that they provide for enhanced specimen management and increase the test ...
David L, McGlasson, George A, Fritsma
openaire   +2 more sources

Current Options in Platelet Function Testing

The American Journal of Cardiology, 2006
The variable response to antiplatelet therapy has led to the use of platelet function tests to monitor the effects of antiplatelet drugs in cardiovascular diseases. The goal is to guide antiplatelet therapy to the optimal dose for the prevention or treatment of thrombosis while minimizing hemorrhagic side effects.
Michelson, Alan D.   +2 more
openaire   +3 more sources

Platelet function testing in pediatric patients

Expert Review of Hematology, 2017
Platelets play a key role in primary hemostasis and are also intricately linked to secondary hemostasis. Investigation of platelet function in children, especially in neonates, is seriously challenged by the volumes required to perform the majority of platelet function tests and due to the lack of standardization of these tests for use in children ...
Hvas, Anne-Mette, Favaloro, Emmanuel J
openaire   +3 more sources

Platelet Function Tests in Bleeding Disorders

Seminars in Thrombosis and Hemostasis, 2016
Functional disorders of platelets can involve any aspect of platelet physiology, with many different effects or outcomes. These include platelet numbers (thrombocytosis or thrombocytopenia); changes in platelet production or destruction, or capture to the liver (Ashwell receptor); altered adhesion to vascular injury sites and/or influence on hemostasis
Lassila Riitta, Lassila Riitta
openaire   +2 more sources

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