Results 241 to 250 of about 171,627 (282)

Tests of platelet function

Current Opinion in Hematology, 2007
Platelets play a vital role in the normal hemostasis, and derangements of their function can lead to hemorrhage or thrombosis. While we have made progress in elucidating the molecular mechanisms leading to platelet adhesion, aggregation, shape change, and secretion, clinically useful tests of platelet function have lagged behind.
Usman, Shah, Alice D, Ma
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Standardization of platelet function tests

American Journal of Hematology, 1981
AbstractMethods for the standardization of several currently used platelet function tests (bleeding time, capillary fragility, platelet retention, platelet aggregation, platelet factor 3, and platelet volume profiles) are presented. Different variables that may interfere with the reproducibility of the results of each assay were identified and ...
P R, Roper-Drewinko, B, Drewinko, G, Corrigan, D, Johnston, K B, McCredie, E J, Freireich   +5 more
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Contemporary platelet function testing

cclm, 2010
Abstract Defects in primary hemostasis typically lead to a bleeding diathesis and include several disorders, such as von Willebrand disease and various platelet function defects that may arise because of failure of membrane receptors, deficiencies in internal storage organelles, and/or signal transduction problems.
Favaloro EJ, LIPPI, Giuseppe, Franchini M.   +2 more
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A new platelet function test

Thrombosis Research, 1990
A method for screening EDTA(K3) blood samples for platelet function is described. The general availability of whole blood platelet counters in the clinical laboratory suggested their use to measure platelet aggregation. To simplify the collection and storage of blood samples, a method utilizing EDTA collected blood is described. Addition of calcium and
W L, Ryan, K, Hakenkamp, E, Sullivan
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Reproducibility of Platelet Function Testing

Laboratory Hematology, 2007
Platelet aggregation and release studies aid in the diagnosis of bleeding disorders. However, variability in normal individuals has not been established. We evaluated the variation in platelet aggregation and release testing over a period of 2 years with 59 observations among 5 subjects.
Megan E, Hevelow, Steven M, McKenzie, Jamie E, Siegel   +2 more
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Platelet Function Tests in Disease

Annual Review of Medicine, 1973
Abnormal platelet function may result from congenital or acquired disturbances in the platelets themselves or their plasma milieu in patients with hemorrhage or thrombosis. Although standardization is difficult and results overlap between patient groups certain tests are abnormal in patients with diabetes and atherosclorosis and in women on oral ...
T B, Tschopp, M B, Zucker
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Platelet function inhibitors and platelet function testing in neurointerventional procedures

Journal of NeuroInterventional Surgery, 2014
Over the past decade there has been a growing use of intracranial stents for the treatment of both ischemic and hemorrhagic cerebrovascular disease, including stents to assist in the remodeling of the neck of aneurysms as well as the use of flow diverting devices for aneurysm treatment.
Chirag D, Gandhi, Ketan R, Bulsara, Johanna, Fifi, Tareq, Kass-Hout, Ryan A, Grant, Josser E, Delgado Almandoz, Joey, English, Philip M, Meyers, Todd, Abruzzo, Charles J, Prestigiacomo, Ciaran James, Powers, Seon-Kyu, Lee, Barbara, Albani, Huy M, Do, Clifford J, Eskey, Athos, Patsalides, Steven, Hetts, M Shazam, Hussain, Sameer A, Ansari, Joshua A, Hirsch, Michael, Kelly, Peter, Rasmussen, William, Mack, G Lee, Pride, Michael J, Alexander, Mahesh V, Jayaraman   +25 more
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Platelets and platelet function testing in children

Progress in Pediatric Cardiology, 2005
Abstract Platelets play key roles in hemostasis as well as in the pathogenesis of arterial thrombosis. This review summarizes current knowledge of the physiology of pediatric platelets; similarities and differences with platelets from adults are discussed with regards to platelet characteristics, adhesion, activation and secretion, and aggregation. A
Margaret L. Rand, Stefan Kuhle
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Whole Blood Platelet Aggregometry and Platelet Function Testing

Seminars in Thrombosis and Hemostasis, 2009
Platelet aggregometry has been the reference method employed to detect, diagnose, and monitor qualitative platelet disorders since the early 1960s. Lumiaggregometry and impedance-based whole blood lumiaggregometry have advantages over light transmittance aggregometry in that they provide for enhanced specimen management and increase the test ...
David L, McGlasson, George A, Fritsma
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Platelet function testing: state of the art

Expert Review of Cardiovascular Therapy, 2007
Platelet function testing has evolved from crude tests, such as the bleeding time, to tests that permit a relatively sophisticated evaluation of platelet activity. Nonetheless, these tests are hampered by lack of specificity and sensitivity, and poor standardization of methods and techniques.
Amer M, Zeidan, Peter A, Kouides, Mary Ann, Tara, William A, Fricke   +3 more
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