Exercise-Derived Microvesicles: A Review of the Literature [PDF]
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent+2 more
core +2 more sources
Platelet glycoprotein VI genetic quantitative and qualitative defects
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for ...
Martine Jandrot-Perrus+2 more
doaj +1 more source
Background: Recent studies have confirmed that patients with unstable angina pectoris (UAP) complicated with diabetes mellitus(DM) have obvious per-thrombosis state.
Jian-lin Ma+6 more
doaj +1 more source
A large deletion in the GP9 gene in Cocker Spaniel dogs with Bernard-Soulier syndrome.
Inherited bleeding disorders including abnormalities of platelet number and function rarely occur in a variety of dog breeds, but are probably underdiagnosed.
Fabio Gentilini+8 more
doaj +1 more source
Recreation of the terminal events in physiological integrin activation. [PDF]
Increased affinity of integrins for the extracellular matrix (activation) regulates cell adhesion and migration, extracellular matrix assembly, and mechanotransduction.
Bobkov, Andrey A+8 more
core +3 more sources
Identification of 22 novel mutations in patients with Glanzmann's thrombasthenia [PDF]
Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect that characterized by reduction in, or absence of, platelet aggregation in response to multiple physiologic agonists. GT is characterized by normal platelet
Abdul Ethayathulla+6 more
core +1 more source
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine+11 more
core +1 more source
An Irreversible Synthetic Route to an Ultra-Strong Two-Dimensional Polymer [PDF]
Polymers that extend covalently in two dimensions have attracted recent attention as a means of combining the mechanical strength and in-plane energy conduction of conventional two-dimensional (2D) materials with the low densities, synthetic processability, and organic composition of their one-dimensional counterparts.
arxiv
Identification of the platelet-specific alloantigen, Naka, on platelet membrane glycoprotein IV [PDF]
Abstract We describe the membrane localization of a new platelet-specific alloantigen, designated Naka, that is involved in refractoriness to HLA- matched platelet transfusions. By indirect immunoprecipitation, anti- Naka antibody precipitated a single, radiolabeled platelet membrane protein with a molecular weight (mol wt) of 91 Kd from
S Sekiguchi+9 more
openaire +3 more sources
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions. [PDF]
Integrin-mediated cell adhesion often results in cell spreading and the formation of focal adhesions. We exploited the capacity of recombinant human alpha IIb beta 3 integrin to endow heterologous cells with the ability to adhere and spread on fibrinogen
Chen, Y+5 more
core