Results 281 to 290 of about 102,308 (347)
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EMBO Journal, 1984
We demonstrate that HEL, a human erythroleukemic cell line, has numerous megakaryocytic markers which were markedly enhanced following the addition of the inducers dimethyl sulfoxide or 12‐O‐tetradecanoylphorbol‐13‐acetate to the culture medium ...
A. Tabilio +7 more
semanticscholar +1 more source
We demonstrate that HEL, a human erythroleukemic cell line, has numerous megakaryocytic markers which were markedly enhanced following the addition of the inducers dimethyl sulfoxide or 12‐O‐tetradecanoylphorbol‐13‐acetate to the culture medium ...
A. Tabilio +7 more
semanticscholar +1 more source
Thrombosis and Haemostasis, 1998
Summary Platelet membrane glycoproteins play a crucial role in ischemic complications after coronary stenting. Glycoprotein IIb-IIIa blockade reduces adverse clinical events after angioplasty but is associated with rare but profound thrombocytopenia that
M. Gawaz +6 more
semanticscholar +1 more source
Summary Platelet membrane glycoproteins play a crucial role in ischemic complications after coronary stenting. Glycoprotein IIb-IIIa blockade reduces adverse clinical events after angioplasty but is associated with rare but profound thrombocytopenia that
M. Gawaz +6 more
semanticscholar +1 more source
Platelet membrane glycoproteins
Thrombosis Research, 1996Inherited giant platelet disorders (IGPD) are a heterogeneous group of rare diseases characterized by thrombocytopenia, large platelets and variable bleeding symptoms. Glycoprotein (GP) expression on platelet surface in these conditions is poorly characterized. We have investigated the expression of constitutively expressed platelet membrane GP and the
Miguel Lozano +5 more
openaire +4 more sources
ASAIO journal (1992), 1993
Changes in platelet membrane glycoproteins (GPIb, GPIIb/IIIa, and GMP-140) were evaluated using flow cytometry after binding with monoclonal antibodies in 22 adult patients undergoing cardiopulmonary bypass (CPB) surgery.
C. Kondo +9 more
semanticscholar +1 more source
Changes in platelet membrane glycoproteins (GPIb, GPIIb/IIIa, and GMP-140) were evaluated using flow cytometry after binding with monoclonal antibodies in 22 adult patients undergoing cardiopulmonary bypass (CPB) surgery.
C. Kondo +9 more
semanticscholar +1 more source
New polymorphism of platelet membrane glycoproteins
Nature, 1977THE surface of the human blood platelet is rich in carbohydrate and at least four glycoprotein components have been resolved by gel electrophoresis of isolated platelet plasma membranes1. Two platelet disease states are characterised by a diminution or absence of certain of these glycoproteins2–5: in the case of Bernard-Soulier disease, glycoprotein I (
R. B. Bolin, G. A. Jamieson, T. Okumura
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Platelets, 2009
Platelets of patients suffering from Glanzmann's thrombasthenia (GT) and Bernard Soulier Syndrome (BSS) are defective in different membrane glycoproteins. Since these integrins can be identified by monoclonal antibodies, normal infused platelets could be
J. César, A. Vecino
semanticscholar +1 more source
Platelets of patients suffering from Glanzmann's thrombasthenia (GT) and Bernard Soulier Syndrome (BSS) are defective in different membrane glycoproteins. Since these integrins can be identified by monoclonal antibodies, normal infused platelets could be
J. César, A. Vecino
semanticscholar +1 more source
Clinical Hemorheology and Microcirculation, 2008
PURPOSE The use of clopidogrel is standard in interventional cardiology. Haemorrhage occurs in some patients, which implies a need for a non-transfusional therapy. Desmopressin showed its efficacy as an antidote of acetylsalicylic acid. In this trial the
B. Leithäuser +3 more
semanticscholar +1 more source
PURPOSE The use of clopidogrel is standard in interventional cardiology. Haemorrhage occurs in some patients, which implies a need for a non-transfusional therapy. Desmopressin showed its efficacy as an antidote of acetylsalicylic acid. In this trial the
B. Leithäuser +3 more
semanticscholar +1 more source
Thrombin Interaction With Platelet Membrane Glycoprotein Ib [PDF]
Seminars in Thrombosis and Hemostasis, 1996 Platelet activation by low doses of thrombin allows the amplification thrombin formation and thereby plays an important role in the development of thrombi. Although thrombin-induced platelet activation is elicited via the cleavage of its specific receptor (TR), platelet membrane glycoprotein Ib (GPIb) is required for responses to low concentrations of ...
Marie-Christine Bouton +3 more
openaire +2 more sources
Polymorphisms of Platelet Membrane Glycoproteins
2009Platelet glycoproteins (GPs) act as membrane receptors. Functions of GPs were well studied in GPIa/IIa (integrin α2β1), GPIb/IX/V, GPIIb/IIIa (integrin αIIbβ3), and GPVI. Each GP has a different role in the processes of physiological hemostasis and thrombus formation, such as platelet adhesion to the subendothelial matrix, firm adhesion with subsequent
Mitsuru Murata +2 more
openaire +2 more sources
Thrombosis and Thrombolysis: Platelet Membrane Glycoproteins
Heart, Lung and Circulation, 2007Over the last quarter of a century, therapy for acute coronary syndromes has rapidly evolved. The major causative factor for acute coronary syndromes, particularly acute myocardial infarction, is now recognised to be coronary thrombosis and therapies using thrombolytic agents to dissolve thrombus or percutaneous coronary interventions (angioplasty and ...
openaire +3 more sources