Results 31 to 40 of about 96,324 (329)
Antibodies against complement-regulatory proteins on platelets in immune thrombocytopenia
Platelets, 2017 In immune thrombocytopenia (ITP), antibodies reacting with platelet membrane glycoproteins (GP) mediate premature platelet cleavage, resulting in thrombocytopenia and therefore a risk of bleeding.
Ursula Unterberger +3 more
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Platelet Apoptosis Can Be Triggered Bypassing the Death Receptors
Clinical and Applied Thrombosis/Hemostasis, 2019 In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane.
Valery Leytin PhD +2 more
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Vaccines, 2023 Kounis syndrome is a multisystem and multidisciplinary disease affecting the circulatory system that can be manifested as spasm and thrombosis. It can occur as allergic, hypersensitivity, anaphylactic, or anaphylactoid reactions associated with the ...
Christos Gogos +7 more
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Pesquisa de anticorpos antiplaquetários. As primeiras cem amostras estudadas.
Acta Médica Portuguesa, 2000 Two types of platelet alloantigens are considered: type I, which refers to platelet alloantigens shared by platelets and other cells; and type II, which comprises the platelet-specific alloantigens.
M M Campos +3 more
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Isolation of Some Platelet Membrane Glycoproteins [PDF]
Thrombosis and Haemostasis, 1977 The platelet is surrounded by a pronounced glycocalix formed by carbohydrate moieties of the membrane glycoproteins. The number of glycoproteins of the outer platelet membrane is greater in number than had previously been reported : when solubilized membranes are analyzed by SDS-polyacrylamide gel electrophoresis the number of separated carbohydrate ...
C. S. P. Jenkins +4 more
openaire +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Platelet glycoprotein (GP) Ⅱ b/Ⅲ a receptor is the final common pathway of platelet aggregation and thrombosis, which can specifically and rapidly inhibit platelet aggregation. In recent years, more and more evidences support that tirofiban, a GP Ⅱ b/Ⅲ a
Xiao⁃chuan HUO, Zhong⁃rong MIAO
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9.5 COAGULATION CONTROL BY THE RHOA PATHWAY AND THE EXCHANGE FACTOR ARHGEF1
Artery Research, 2016 Platelet activation by thrombin is an auto-amplification loop of thrombin generation, a major factor in the formation of atherosclerotic plaques. The small G protein RhoA, under the direct control of the exchange factor Arhgef1, modulates several ...
Camille Rouillon +4 more
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Autophagy in Extracellular Matrix and Wound Healing Modulation in the Cornea
Biomedicines, 2022 Autophagy is a robust cellular mechanism for disposing of harmful molecules or recycling them to cells, which also regulates physiopathological processes in cornea.
Duraisamy Kempuraj, Rajiv R. Mohan
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Nix-mediated mitophagy regulates platelet activation and life span
Blood Advances, 2019 : Platelet activation requires fully functional mitochondria, which provide a vital energy source and control the life span of platelets. Previous reports have shown that both general autophagy and selective mitophagy are critical for platelet function ...
Weilin Zhang +9 more
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HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source