Results 31 to 40 of about 40,970 (289)

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Blood Transfusion Components Inducing Severe Allergic Reactions: The First Case of Kounis Syndrome Induced by Platelet Transfusion

Vaccines, 2023
Kounis syndrome is a multisystem and multidisciplinary disease affecting the circulatory system that can be manifested as spasm and thrombosis. It can occur as allergic, hypersensitivity, anaphylactic, or anaphylactoid reactions associated with the ...
Christos Gogos, Konstantinos Stamos, Nikolaos Tsanaxidis, Ioannis Styliadis, Ioanna Koniari, Sophia N. Kouni, Cesare de Gregorio, Nicholas G. Kounis   +7 more
doaj   +1 more source

Pesquisa de anticorpos antiplaquetários. As primeiras cem amostras estudadas.

Acta Médica Portuguesa, 2000
Two types of platelet alloantigens are considered: type I, which refers to platelet alloantigens shared by platelets and other cells; and type II, which comprises the platelet-specific alloantigens.
M M Campos, E Fernández, M J Marques, A Cordeiro   +3 more
doaj   +1 more source

A fibronectin-binding glycoprotein from human platelet membranes [PDF]

Biochemical Journal, 1981
Fibronectin (‘cold-insoluble globulin’) has been suggested as a possible mediator of platelet adhesion. A fibronectin-binding protein as partially purified from washed solubilized human platelet membranes by affinity chromatography on fibronectin-Sepharose.
M S, Hansen, I, Clemmensen
openaire   +2 more sources

Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts [PDF]

, 1998
Beside the major effect of acute thrombus formation, little is known about the interaction of platelets with the coronary endothelium in an ischaemia–reperfusion situation.
Alloatti, Altieri, Bünger, Capron, Chang, Coker, Conforti, Cook, D'Souza, Dauber, Dreyer, Gilbert, Goulielmos, Grover, Hicks, Hoshiga, Kowalski, Kupatt, Languino, Mannaionini, Mogford, Möbert, Rodgers, Rousseau, Rubboli, Rösen, Sheppeck, Sheridan, Sixma, Swerlick, Takiguchi, Wheatley, Yang, Yang, Yang, Zahler   +35 more
core   +1 more source

Consensus interpretation on "Expert consensus on clinical application of tirofiban in atherosclerotic cerebrovascular disease"

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Platelet glycoprotein (GP) Ⅱ b/Ⅲ a receptor is the final common pathway of platelet aggregation and thrombosis, which can specifically and rapidly inhibit platelet aggregation. In recent years, more and more evidences support that tirofiban, a GP Ⅱ b/Ⅲ a
Xiao⁃chuan HUO, Zhong⁃rong MIAO
doaj  

9.5 COAGULATION CONTROL BY THE RHOA PATHWAY AND THE EXCHANGE FACTOR ARHGEF1

Artery Research, 2016
Platelet activation by thrombin is an auto-amplification loop of thrombin generation, a major factor in the formation of atherosclerotic plaques. The small G protein RhoA, under the direct control of the exchange factor Arhgef1, modulates several ...
Camille Rouillon, Amel Mohammadi, Gervaise Loirand, Veronique Regnault, Patrick Lacolley   +4 more
doaj   +1 more source

Autophagy in Extracellular Matrix and Wound Healing Modulation in the Cornea

Biomedicines, 2022
Autophagy is a robust cellular mechanism for disposing of harmful molecules or recycling them to cells, which also regulates physiopathological processes in cornea.
Duraisamy Kempuraj, Rajiv R. Mohan
doaj   +1 more source

Nix-mediated mitophagy regulates platelet activation and life span

Blood Advances, 2019
: Platelet activation requires fully functional mitochondria, which provide a vital energy source and control the life span of platelets. Previous reports have shown that both general autophagy and selective mitophagy are critical for platelet function ...
Weilin Zhang, Qi Ma, Sami Siraj, Paul A. Ney, Junling Liu, Xudong Liao, Yefeng Yuan, Wei Li, Lei Liu, Quan Chen   +9 more
doaj   +1 more source

Translocating the blood-brain barrier using electrostatics [PDF]

, 2012
Copyright © 2012 Ribeiro,Domingues, Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the ...
Castanho, Miguel A. R. B., Domingues, Marco M., Freire, João M., Ribeiro, Marta M. B., Santos, Nuno C.   +4 more
core   +2 more sources