Results 21 to 30 of about 206,755 (278)
Frontiers in Immunology, 2023 Patients with hematological disorders and severe thrombocytopenia require extensive and iterative platelet transfusion support. In these patients, platelet transfusion refractoriness represents a serious adverse transfusion event with major outcomes for ...
Adèle Couvidou +15 more
doaj +3 more sources
Asian Journal of Transfusion Science, 2015 Background: This study was designed to determine the prevalence and assess the risk factors responsible for platelet transfusion refractoriness in hemato-oncological patients. Materials and Methods: The study included 30 patients.
Vijay Kumawat +3 more
doaj +2 more sources
Prevalence and Specificity of Anti-HPA and Anti-HLA Antibodies in Patients with Suspected Immune-Mediated Platelet Disorders: A Single-Center Study from Serbia [PDF]
MedicinaBackground and Objectives: Alloantibodies directed against human platelet antigens and human leukocyte antigens are implicated in several immune-mediated platelet disorders, including platelet transfusion refractoriness, post-transfusion purpura and ...
Svetlana Vojvodić, Jasmina Grujić
doaj +2 more sources
Platelet Transfusion Refractoriness
PlasmatologyPlatelet transfusion refractoriness (PTR) is a conditioikb1n where platelet counts fail to increase adequately in several transfusions, often found in hemato-oncological situations.
Anna Mira Lubis MD +2 more
doaj +2 more sources
Educational Case: Platelet refractoriness. [PDF]
Acad Pathol, 2022 Griffith AJ, Rose WN.
europepmc +3 more sources
Frontiers in Medicine, 2023 ObjectiveTransfusion of HLA-matched platelets can reduce the effect of alloimmune responses on platelet transfusion efficacy; however, finding HLA-matched platelets in the population is nearly impossible. Almost all HLA-matched platelets from related are
Jing-Cheng Zhang +3 more
doaj +3 more sources
International Journal of General Medicine, 2017 Meera Chitlur,1 Madhvi Rajpurkar,1 Michael Recht,2 Michael D Tarantino,3 Donald L Yee,4 David L Cooper,5 Sriya Gunawardena5 1Carman and Ann Adams Department of Pediatrics, Wayne State University and Children’s Hospital of Michigan, Detroit, MI, USA;
Chitlur M +6 more
doaj +1 more source
The use of splenectomy to manage platelet transfusion refractoriness due to anti-human leukocyte antibodies in allogeneic stem cell transplantation [PDF]
Pediatric Reports, 2016 In patients undergoing hematopoietic stem cell transplantation (HSCT), refractoriness to platelet transfusion has been associated with graft failure, delayed engraftment, early mortality and decreased overall survival.
Margherita Mauro +6 more
doaj +2 more sources
Case Study: HLA incompatible platelet infusion to allow emergency salvage HCT in a patient with primary graft failure due to donor specific HLA antibody [PDF]
Frontiers in ImmunologyA patient with myelodysplasia received a haploidentical hematopoietic stem cell transplant (HCT). Pre-transplant HLA antibody screening showed no detectable donor-specific antibodies (DSAs). Post-transplant, the patient developed an anti-HLA-A2 antibody,
Louise Goddard +3 more
doaj +2 more sources
Chronic Immune Platelet Activation Is Followed by Platelet Refractoriness and Impaired Contractility. [PDF]
Int J Mol Sci, 2022 Autoimmune diseases, including systemic lupus erythematosus (SLE), have a high risk of thrombotic and hemorrhagic complications associated with altered platelet functionality. We studied platelets from the blood of SLE patients and their reactivity.
Andrianova IA +8 more
europepmc +2 more sources