Results 31 to 40 of about 206,755 (278)

Platelet transfusion: basic aspects

Swiss Medical Weekly, 2013
Platelet transfusions have been shown to prevent major haemorrhage and improve survival in thrombocytopenic patients. Since then, advances in the preparation of platelet components, including the introduction of pathogen reduction techniques, have ...
Andreas Holbro, Laura Infanti, Jörg Sigle, Andreas Buser   +3 more
doaj   +2 more sources

Platelet Refractoriness in a Pediatric ECMO Patient: A Case Report. [PDF]

J Extra Corpor Technol, 2019
Thrombocytopenia is a life-threatening condition, the severity of which is exacerbated further if the patient requires anticoagulation and is refractory to platelet transfusion. This is the first report of an infant undergoing extracorporeal support with
Gill M.
europepmc   +2 more sources

Risk Factors of Platelet Refractoriness After Thrombocyte Concentrate Transfusion in Pediatric Acute Leukemia [PDF]

, 2022
Children with acute leukemia often require platelet transfusions, but the platelet count frequently doesn't reach a satisfactory response, which is known as platelet refractoriness. This study aimed to analyze the risk factors for platelet refractoriness
Hosea, M. K. (Mellisa), Wardhani, A. N. (Adwina), Ugrasena, I. D. (I), Andarsini, M. R. (Mia), Larasati, M. C. (Maria), Cahyadi, A. (Andi)   +5 more
core   +2 more sources

Mechanism and transfusion strategy of immunogenic platelet transfusion refractoriness

Zhongguo shuxue zazhi, 2022
Platelet transfusion is an irreplaceable method to treat patients with platelet reduction in Hematology Department and Oncology Department. However, immunogenic platelet transfusion refractoriness is a huge challenge to patients who require repeatedly ...
Juan SAI, Li TIAN
doaj   +1 more source

Prevalence, Risk Factors, and Outcomes of Platelet Transfusion Refractoriness in Critically Ill Patients: A Retrospective Cohort Study

Critical Care Research and Practice, 2021
Background. Refractoriness to platelet transfusion is an understudied phenomenon in critically ill patients. Our objective was to evaluate the prevalence, risk factors, and clinical outcomes of platelet refractoriness among patients in a tertiary-care ...
Saeed Arabi, Abdullah O. Almahayni, Abdulrahman A. Alomair, Emad M. Masuadi, Moussab Damlaj, Hasan M. Al-Dorzi   +5 more
doaj   +1 more source

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets

Haematologica, 2022
Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA).
Thijs L.J. van Osch, Janita J. Oosterhoff, Arthur E. H. Bentlage, Jan Nouta, Carolien A. M. Koeleman, Dionne M. Geerdes, Juk Yee Mok, Sebastiaan Heidt, Arend Mulder, Wim J. E. van Esch, Rick Kapur, Leendert Porcelijn, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer, Jan Voorberg, Gestur Vidarsson   +16 more
doaj   +1 more source

Extent of transfusion support in a developing country in managing a bleeding acute myeloid leukemia patient with platelet transfusion refractoriness

Asian Journal of Transfusion Science, 2021
Conventional platelet transfusion may not be adequate to deal with platelet transfusion refractoriness (PTR), and therefore human leukocyte antigen (HLA) or human platelet antigen (HPA) matched and platelet crossmatch compatible units are recommended ...
Gayathiri K Chellaiya, Chandran K Nair, Vineetha Raghavan, R Jesu Pandian, Roshan Vinod, Mohandoss Murugesan   +5 more
doaj   +1 more source

HLA-Mediated Platelet Refractoriness [PDF]

American Journal of Clinical Pathology, 2018
To provide an overview of the complexities associated with the human leukocyte antigen (HLA)-mediated platelet refractoriness. HLA antibody detection technologies and limitations associated with methodologies are discussed.A case scenario and review of relevant literature describing platelet refractoriness are presented, followed by a discussion of HLA
Amy E, Schmidt, Majed A, Refaai, Myra, Coppage   +2 more
openaire   +2 more sources

Evaluation of the effectiveness of platelet crossmatching by the solid‐phase red cell adherence assay in adult patients of a tertiary care hospital in Thailand: A retrospective study

Health Science Reports, 2022
Background and Aims Platelet transfusion refractoriness is well aware to be associated with poor clinical outcomes. Patients with the alloantibody causing refractoriness required cross‐matched compatible products to improve the platelet number.
Thunnakhon Sinwatcharaphirom, Kusuma Apisawes, Janejira Kittivorapart   +2 more
doaj   +1 more source

Prevalence and Factors associated with Platelet Refractoriness among Tanzanian Patients – A Cross-Sectional Study from The National Reference Hospital [PDF]

, 2023
Background A response to platelet transfusion is assessed by post transfusion platelet increment and failure to reach a desired increment is termed platelet refractoriness, which is best measured by the corrected count increment (CCI) which takes into ...
Luhulla, Koga Malunguja, Nasser, Ahlam, Chamba, Clara, Kakumbula, Helen, Iversen, Per Ole   +4 more
core   +1 more source