Results 91 to 100 of about 3,449 (222)

In Lysinuric Protein Intolerance system y+L activity is defective in monocytes and in GM-CSF-differentiated macrophages [PDF]

open access: yes, 2010
In the recessive aminoaciduria Lysinuric Protein Intolerance (LPI), mutations of SLC7A7/y+LAT1 impair system y+L transport activity for cationic amino acids.
Amelia Barilli   +10 more
core   +1 more source

Comparative evaluation of blood component preparation with the top‐and‐top and top‐and‐bottom methods: A change in Uruguay

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Hospital de Clínicas, in conjunction with the Universidad de la República UDELAR in Uruguay, evaluated the quality of blood components after separation with a top‐and‐bottom (TB) system, comparing it with the top‐and‐top (TT) system and verifying compliance with local and international standards. Study Design and Methods Whole blood
Natalia Méndez Acosta   +5 more
wiley   +1 more source

Transfusão de plaquetas: do empirismo ao embasamento científico Platelet transfusion: from empiricism to scientific evidence

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2010
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion ...
Aline A. Ferreira   +3 more
doaj   +1 more source

Ersatzes of Fetal Bovine Serum: a survey of current options in cell culture: Example of the Regenerative Therapy Unit/CPR/CHUV [PDF]

open access: yes, 2014
Cell culture began in the 19th-century when a physiologist, Sydney Ringer, developed a solution capable of maintaining a beating frog heart outside of the body.
WENGER, N.
core  

Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response

open access: yesTransfusion, EarlyView.
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn   +14 more
wiley   +1 more source

Platelet HLA gene bank digital matching technology for platelet transfusion refractory patients with malignant tumors: a case report

open access: yesFrontiers in Oncology
The platelet human leucocyte antigen (HLA) gene bank contains the genetic information of HLA loci in a large number of blood donors. Currently, the most effective treatment for platelet transfusion refractoriness (PTR) is to evaluate the probability of ...
Xiang Gao   +5 more
doaj   +1 more source

Cytomegalovirus immunity in allogeneic marrow grafting [PDF]

open access: yes, 1985
Contains fulltext : 4452.pdf (publisher's version ) (Open ...
Amaro, J. D'   +9 more
core   +1 more source

Platelet antibody detection by flow cytometry: an effective method to evaluate and give transfusional support in platelet refractoriness [PDF]

open access: yes, 2015
BACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies.
Avelino, Thayna Mendonca   +5 more
core   +2 more sources

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

open access: yesTransfusion, EarlyView.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza   +11 more
wiley   +1 more source

Diagnostic tool for Glanzmann\u27s thrombasthenia clinicopathologic spectrum [PDF]

open access: yes, 2008
OBJECTIVE: To platelet aggregometry and describe the clinical spectrum of Glanzmann\u27s thrombasthenia diagnosed by platelet aggregometry. STUDY DESIGN: A case-series.
Adil, Salman   +5 more
core   +1 more source

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