Results 111 to 120 of about 2,118 (199)
Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu +5 more
doaj
ABSTRACT This multicenter retrospective study aimed to describe temporal trends in clinical indications for plasma exchange (PE) in adult patients at four quaternary‐care hospitals in Bogotá (2008–2024) and to examine their distribution across successive ASFA guideline editions.
Edgar Julián Reyes +7 more
wiley +1 more source
Platelet transfusion refractoriness: how do I diagnose and manage? [PDF]
Cohn CS.
europepmc +1 more source
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome. Epstein–Barr virus (EBV)‐associated HLH is a major subtype of secondary HLH, requiring prompt diagnosis and treatment. However, treatment is particularly challenging in patients with severe coagulopathy and hepatic dysfunction.
Kuniaki Maehara +5 more
wiley +1 more source
ABSTRACT Pancytopenia accompanied by chimeric antigen receptor T cell (CAR‐T) therapy is termed immune effector cell‐associated hematopoietic toxicity (ICAHT), which is often sustained and refractory to supportive care. We report a case of a 52‐year‐old man with multiple myeloma who developed severe ICAHT with secondary myelofibrosis (sMF) after ...
Keishi Ogura +9 more
wiley +1 more source
Immune platelet transfusion refractoriness in pediatric patients undergoing HSCT
Background Children who undergo hematopoietic stem cell transplantation (HSCT) sometimes have immune platelet transfusion refractoriness (IPTR). The thrombopoietin receptor agonist (TPO-RA) is used to increase platelet counts in a variety of immune ...
Olivera Serbic +4 more
doaj +1 more source
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley +1 more source
Restorative versus non‐restorative total proctocolectomy: Who doesn't pouch and how do they do?
Abstract Aim Literature comparing total proctocolectomy with permanent end ileostomy (TPC‐EI) and IPAA in patients with UC is sparse. We aimed to (a) elucidate reasons for non‐restorative surgery in ulcerative colitis (UC), (b) describe the incidence of perineal wound complications and (c) assess differences in short‐term outcomes between groups.
Imran Khan +7 more
wiley +1 more source
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala +14 more
wiley +1 more source
A pilot trial of complement inhibition using eculizumab to overcome platelet transfusion refractoriness in human leukocyte antigen allo-immunized patients. [PDF]
Vo P +14 more
europepmc +1 more source

