Results 111 to 120 of about 48,011 (239)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 389-396, June 2026.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Alloimmune platelet refractoriness [PDF]

open access: yes
En la actualidad, la transfusión de plaquetas, es considerado el tratamiento estándar en pacientes con trombocitopenia, siendo el concentrado plaquetario, el hemocomponente transfundido con mayor frecuencia.
Ancajima Ballena, Maria Elena
core  

Survey of current practice for monitoring and management of platelet refractoriness in Italy.

open access: yes, 2012
Platelet transfusion failure is a common phenomenon affecting from 7% to 34% of haematology-oncology patients. Monitoring the efficacy of platelet transfusion through the evaluation of a post-transfusion platelet count and clinical response represent an ...
Antonio Nicolucci   +5 more
core   +1 more source

Expert Consensus on the Clinical Application of Poly ADP Ribose Polymerase Inhibitors in Breast Cancer (2025 Edition)

open access: yesCancer Innovation, Volume 5, Issue 3, June 2026.
This consensus, based on the latest evidence‐based medical data, provides guidance on the standardized application and safety management of PARP inhibitors in breast cancer treatment, aiming to serve as a reference for clinical practice. ABSTRACT Breast cancer represents a major threat to women's health in China.
Fei Ma   +5 more
wiley   +1 more source

Jejunal Diverticulosis as a Rare Cause of Severe Obscure Gastrointestinal Bleeding in an Elderly Patient: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Jejunal diverticulosis is a rare cause of obscure gastrointestinal bleeding (OGIB) that can present with life‐threatening hemorrhage. We report a 69‐year‐old male with recurrent melena, severe anemia, and hemodynamic instability requiring multiple transfusions. Upper and lower endoscopy were nondiagnostic, and CT angiography failed to localize
Mahmoud Draidi   +5 more
wiley   +1 more source

Pancytopenia With Hypocellular Bone Marrow Revealing Extrahepatic Portal Venous Obstruction and Cavernous Transformation in a Child: A Case Report of a Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Extrahepatic portal venous obstruction (EHPVO) is a leading cause of prehepatic portal hypertension in children, particularly in developing countries. While upper gastrointestinal bleeding is the most common presentation, EHPVO may rarely manifest predominantly with hematological abnormalities due to hypersplenism, posing a diagnostic ...
Swekchha Adhikari   +6 more
wiley   +1 more source

EHA Guidelines on management of chronic lymphocytic leukemia and Richter transformation

open access: yesHemaSphere, Volume 10, Issue 6, June 2026.
Abstract Previous editions of the European guidelines for the management of chronic lymphocytic leukemia (CLL) were developed by experts in CLL under the auspices of the European Society for Medical Oncology (ESMO). These previous editions have served as a reference text for many physicians caring for patients with CLL.
Barbara Eichhorst   +13 more
wiley   +1 more source

Platelet Refractoriness in a Pediatric ECMO Patient: A Case Report

open access: yes, 2019
Thrombocytopenia is a life-threatening condition, the severity of which is exacerbated further if the patient requires anticoagulation and is refractory to platelet transfusion. This is the first report of an infant undergoing extracorporeal support with
Martin Gill
core   +1 more source

Bleeding risk and platelet transfusion refractoriness in patients with acute myelogenous leukemia who undergo autologous stem cell transplantation.

open access: yes, 2000
Therapy for acute myelogenous leukemia can be complicated by alloimmunization to histocompatibility antigens (HLA), with resultant refractoriness to platelet transfusions.
Little, J A, Toor, Amir, MD, Choo, S Y
core  

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