Results 121 to 130 of about 48,011 (239)

Post‐transfusion platelet responses in critically ill cancer patients with hypoproliferative thrombocytopenia

, 2020
International audienceBACKGROUND: Platelet transfusion is aimed at increasing platelet counts to prevent or treat bleeding. Critically ill cancer patients with hypoproliferative thrombocytopenia are high consumers of blood products.
François, Anne, Jamme, Matthieu, Jean‐Daniel Chiche, Julien Charpentier, Alain Cariou, Pène, Frédéric, Elodie Baron, Jean‐Paul Mira, Habib Ben Hadj Amor, Chiche, Jean Daniel, Bassem Habr, Ben Hadj Amor, Habib, Mira, Jean Paul, Cariou, Alain, Charpentier, Julien, Habr, Bassem, Anne François, Frédéric Pène, Matthieu Jamme, Baron, Ėlodie   +19 more
core   +1 more source

Single‐Agent Selinexor Versus Physician's Choice in Previously Treated Myelofibrosis: Results From the Phase 2 XPORT‐035 Study

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Janus kinase inhibitors (JAKis), the current standard of care for myelofibrosis (MF), provide clinical benefit, but responses are frequently incomplete, non‐durable, and associated with cytopenias, underscoring the need for therapies with novel mechanisms of action.
Sebastian Grosicki, Habte Yimer, Rosa Ayala, Suning Chen, Hong Liu, Françoise Boyer, Paola Guglielmelli, Marco Brociner, Paolo Sportoletti, Gabor Mikala, Panagiotis Tsirigotis, Jin Zhang, Tomer Mark, Yi Chai, Andrea Ellero, Alessandro Lucchesi   +15 more
wiley   +1 more source

Leukofiltration plus pathogen reduction prevents alloimmune platelet refractoriness in a dog transfusion model

, 2017
Key Points Eight weekly transfusions of F-LR + pathogen-reduced donor platelets were accepted by 31 of 32 (97%) recipient dogs. Among accepting recipients, none developed lymphocyte and only 2 had platelet antibodies not associated with ...
S. Lawrence Bailey, Todd Christoffel, Sherrill J. Slichter, Irena Gettinger, Karen Nelson, Lakshmi Gaur, Doug Bolgiano, Esther Pellham, Yvette Latchman   +8 more
core   +1 more source

Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Frontiers in Immunology
Patients with transfusion-dependent thalassemia (TDT) are at high risk of alloimmunization. While previous research is predominantly focused on red blood cell alloimmunization, the potential risks of platelet alloimmunization are frequently ...
Yuchen Huang, Yuxi Chen, Qiuhong Mo, Huihui Mo, Fang Lu, Hengcong Li, Lilan Li, Jierun Chen, Lihong Jiang, Yan Zhou, Zhoulin Zhong   +10 more
doaj   +1 more source

Efficacy and Safety of Azacitidine Combined With Lisaftoclax in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome With Increased Blasts

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Objective To retrospectively analyze the early efficacy and safety of azacitidine plus lisaftoclax in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome with increased blasts (MDS‐IB), providing a reliable clinical reference.
Shan Meng, Wanhong Zhao, Hui Zhang, Bo Lei, Wanggang Zhang, Yilin Zhang, Jin Wang, Yinxia Chen, Xingmei Cao, Liufang Gu   +9 more
wiley   +1 more source

A Case Report of Shwachman‐Diamond Syndrome Caused by Heterozygous Variants in the EFL1 Gene and Literature Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
We report a neonatal SDS patient with earliest onset of symptoms. The c.2935C>T and c.3149_3151delCAC compound heterozygous variants reported in this study expand the mutational spectrum of this disease. ABSTRACT Objective This investigation reports on a Shwachman‐Diamond syndrome (SDS) case arising from compound heterozygous genetic variations ...
Xiaoying Zhou, Hongxin Li, Xinyi Yang, Chunli Wang, Wenting Zhang   +4 more
wiley   +1 more source

Antiplatelet antibodies in patients with ITP and patient with platelet refractoriness

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Background: Immune thrombocytopenic purpura is an acquired disorder, in which accelerated platelet consumption is due to PLT autoantibodies. The diagnosis of immune thrombocytopenic purpura is a diagnosis of exclusion.
Salah Aref, Lamiaa Ebrahim, Tarek Selim
doaj  

[Chinese expert consensus on the diagnosis and management of platelet transfusion refractoriness (2022)]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2022
Chinese Society of Hematology, Chinese Medical Association.   +1 more
europepmc   +1 more source

Post‐Transfusion Purpura: A Clinical Case With Alveolar Haemorrhage

Respirology Case Reports, Volume 14, Issue 6, June 2026.
We report a case of post‐transfusion thrombocytopenic purpura and alveolar haemorrhage in a woman after knee replacement surgery, occurring 7 days after transfusion of 20 mL of blood. This case was successfully treated with therapeutic plasma exchange and intravenous immunoglobulin.
Yordanka Yamakova, Aleksandar Pisanchev, Aleksandar Farfarov, Rosen Petkov   +3 more
wiley   +1 more source

FREQUENCY AND CHARACTERIZATION OF PLATELET- SPECIFIC ANTIBODIES IN PATIENTS WHO RECEIVED MULTIPLE PLATELET TRANSFUSIONS [PDF]

, 2000
Multiple platelet transfusions can induce alloimmunization. Alloimmunization involving platelet membrane antigens has been characterized by failure to achieve the expected post-transfusion platelet levels; this is a clinical status frequently referred to
Susannah Whay-Sue Lin, Jhy-Sheng Chang, Shyh-Chyi Lo, Dong-Tsamn Lin   +3 more
core