Lung‐Cardiovascular Interactions and Derangements in ARDS
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez +4 more
wiley +1 more source
After delivery: How recipient cells shape the fate and function of transplanted mitochondria
Recipient‐cell handling shapes how transplanted mitochondria contribute after delivery, linking donor competence, recipient state and exposure duration to intracellular fate. The framework matches transient rescue, sustained functional support and durable mitochondrial DNA correction to the evidence and product attributes required for each therapeutic ...
Zhi‐Yuan Zhang +3 more
wiley +1 more source
Clinical and immunological features of platelet transfusion refractoriness in young patients with de novo acute myeloid leukemia. [PDF]
Hu X +11 more
europepmc +1 more source
ABSTRACT Background and Aims Since the discovery of major blood groups, the potential relationship between blood groups and various diseases has garnered interest. Most studies in this area have focused on adults, with comparatively fewer related to children, particularly newborns.
Seyyed Mohammad Hassan Aletayeb +4 more
wiley +1 more source
Personalized management of platelet transfusion refractoriness: risk factors, cross-matching, and IVIG strategies. [PDF]
Li J +7 more
europepmc +1 more source
A pilot trial of complement inhibition using eculizumab to overcome platelet transfusion refractoriness in human leukocyte antigen allo-immunized patients. [PDF]
Vo P +14 more
europepmc +1 more source
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness. [PDF]
Ziza K +11 more
europepmc +1 more source
ABSTRACT Chronic limb‐threatening ischemia (CLTI), a severe manifestation of peripheral artery disease, is particularly prevalent among patients receiving maintenance hemodialysis (HD) and is associated with poor limb and survival outcomes. Low‐density lipoprotein (LDL) apheresis, including Rheocarna, is used as adjunctive therapy for refractory CLTI ...
Yusuke Ishizuka +14 more
wiley +1 more source
Beyond HLA: an exploratory pilot study of non-HLA antibodies, HLA sensitization, and GSTT1 genotype in platelet transfusion refractoriness. [PDF]
Qi J +10 more
europepmc +1 more source

