Results 151 to 160 of about 291,220 (220)

Platelet reactive alloantibodies responsible for immune thrombocytopenia in Malay population

Background: Alloantibodies against human platelet alloantigens (HPAs) are responsible for the development of platelet transfusion refractoriness (PTR) in patientsreceiving random platelets and bleeding disorder in babies with fetal neonatal alloimmune ...
Afifah Hassan, Hevi Wihadmadyatami, Sentot Santoso, Mohd I. Armawai   +3 more
core  

Evaluation of the provision of crossmatch compatible platelets for haematology patients who have acquired non-immune refractoriness

Platelet demand is unpredictable and will relate to case mix, programmes of treatment requiring intensive platelet support and health service activity.
Samantha J. Reynolds (24033552)
core   +1 more source

Plasma Exchange for Hantavirus Pulmonary Syndrome: A Mechanistic Case for an Untested Intervention

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Hantavirus pulmonary syndrome (HPS) carries a case fatality rate of 35%–40% and has no approved pharmacologic treatment. Its pathophysiology is rooted in the plasma compartment: cytokines, viral antigens, immune complexes, and platelet‐binding glycoproteins circulate as drivers of immunopathologic endothelial injury, noncardiogenic pulmonary ...
Menatalla Nadim, Yasamin Mirzabeigi, Yamac Akgun   +2 more
wiley   +1 more source

Platelet desialylation, apoptosis, and T-lymphocyte-mediated immune dysregulation: unveiling the pathways of platelet clearance in platelet transfusion refractoriness. [PDF]

Res Pract Thromb Haemost
Zhou Y, Zhong Z, Mo H, Liang L, Su C, Chen Y, Lu F, Huang Y, Wu G.   +8 more
europepmc   +1 more source

Plerixafor and G‐CSF Versus Placebo and G‐CSF in Moderately Mobilizing Patients With Multiple Myeloma to Optimize Hematopoietic Stem Cell Collection Results (OPTIMIZE)

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Efficient collection of hematopoietic progenitor cells (HPCs) is essential for autologous stem cell transplantation (ASCT) in multiple myeloma (MM). Although plerixafor is routinely used in poor mobilizers, its role in patients with intermediate mobilization capacity remains unclear.
Worel Nina, Schreder Martin, Tanzmann Andreas, Kurz Martin, Huber‐Kraßnitzer Bianca, Neumeister Peter, Rosskopf Konrad, Sareban Nazanin, Branka Manuela, Kolovratova Vera, Oesterreicher Sophia, Koerbler Beatrix, Kitzweger Elvira, Ruckser Reinhard, Rabitsch Werner, Agis Hermine, Krauth Maria, Greinix Hildegard T.   +17 more
wiley   +1 more source

Marked platelet transfusion refractoriness caused by anti-HLA-I and anti-HPA-5b antibodies: A case report. [PDF]

Medicine (Baltimore)
Wang Y, Liu Z, Duan S, Lin C, Jin Y, Wang H, Wang Y, Tang L, Wang M.   +8 more
europepmc   +1 more source

Atypical Presentation of UBE2T‐Related Fanconi Anemia With Immune‐Mediated Thrombocytopenia and Hematopoietic Somatic Mosaicism: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Fanconi anemia (FA) is a genetically heterogeneous disorder of chromosome instability leading to bone marrow failure (BMF) and other manifestations. We report a case of FA in which two atypical features initially obscured the diagnosis: the presence of T cell‐mediated thrombocytopenia, and somatic mosaicism leading to normal chromosome ...
Bridget T. Kiely, Alison A. Bertuch
wiley   +1 more source

When Liver Disease Misleads the Diagnosis: Two Cases of TAFRO Syndrome With Porto‐Sinusoidal Vascular Disease

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background TAFRO syndrome is a rare inflammatory disorder whose hepatic manifestations may mimic decompensated cirrhosis. Cases: We report two women with TAFRO syndrome associated with portal‐sinusoidal vascular disorder (PSVD), a rare cause of non‐cirrhotic portal hypertension. In both cases, liver biopsy excluded cirrhosis and confirmed PSVD.
Laura Dassy, Fanny Poletti, Kaoutar Hafraoui, Marie Lejeune, Joan Somja, Patrick Collins, Julien Guiot, Ivan Theate, Jo Caers, Jean Delwaide, Astrid Marot, Virginie Putzeys, Gaëlle Vertenoeil   +12 more
wiley   +1 more source

Repeated Response to Daratumumab in Refractory MGUS‐Associated Pure Red Cell Aplasia Persisting After Allogeneic Transplantation: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Pure red cell aplasia (PRCA) is usually managed as a disorder driven predominantly by cellular immune mechanisms, but plasma cell‐directed therapy may be relevant in selected cases associated with monoclonal gammopathy. We report a case of refractory PRCA associated with IgG‐kappa monoclonal gammopathy of undetermined significance (MGUS). A 64‐
Kyoko Yoshihara, Toshimitsu Matsui, Ikuo Matsuda, Mami Samori, Yoshiyuki Fujita, Saki Takahashi, Fuyuki Yamagata, Nobuto Utsunomiya, Chisato Ohe, Satoshi Yoshihara   +9 more
wiley   +1 more source

Platelet transfusion refractoriness within one month post-hematopoietic stem cell transplantation does not impair survival in aplastic anemia patients after engraftment: a propensity score-matched analysis. [PDF]

Front Immunol
Wang Y, Zhang Y, Liu L, Zhang T, Sun J, Chen X, Yang D, Pang A, Zhang R, Ma Q, Zhai W, He Y, Wei J, Cao Y, Liang C, Jiang E, Han M, Feng S.   +17 more
europepmc   +1 more source