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Challenge of Alloimmunization and Refractoriness to Platelet Transfusion
1997Alloimmunization and refractoriness to platelet transfusion remains the major problem following repeated platelet transfusions. Approaches to donor selection for alloimmunized recipients include a variety of strategies for HLA matching and platelet crossmatching of random donor units of platelet concentrates as a means of identifying new compatible ...
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Strategies for managing refractoriness to platelet transfusions.
Current hematology reports, 2003The availability of platelet transfusions made possible intensive, myelosuppressive therapy. Chronic transfusion support is often complicated by refractoriness to platelet transfusions characterized by inadequate post-transfusion platelet count increments. Refractoriness is most commonly associated with a variety of clinical factors.
Maria E, Dan, Charles A, Schiffer
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Refractoriness to Platelet Transfusions
American Journal of Clinical Pathology, 1989openaire +2 more sources
Non-Alloimmune Mechanisms of Thrombocytopenia and Refractoriness to Platelet Transfusion
Transfusion Medicine Reviews, 2020Roger Belizaire
exaly
Severe Platelet Transfusion Refractoriness in Association with Antibodies Against CD36
Laboratory Medicine, 2020Majed Refaai +2 more
exaly
[Platelet transfusion refractoriness and effective management of platelet alloimmunization].
Nihon rinsho. Japanese journal of clinical medicine, 1997Platelet transfusion recipients become alloimmunized to foreign HLA and HPA antigens, impairing their responses to further platelet transfusions (platelet transfusion refractoriness; PTR). Anti-HLA and HPA antibodies account for the majority of clinically significant alloimmunizations.
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